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01.Glia and Inflammation in Neurodegenerative Disease
02.Chronic Granulomatous Disease: Genetics, Biology and Clinical Management
03.Antibiotic Resistance: Causes and Risk Factors, Mechanisms and Alternatives
04.New Developments in Blood Transfusion Research
05.Mast Cells: Roles, Interactions and Disorders
06.Molecular Mechanisms of Tobacco-Induced Diseases
07.Focus on Vitamin E Research
08.Microwave Applications in Pathology
09.Hereditary Immunity: Fundamental Principles and Exploitation in Life Study and Health Care
10.DNA Vaccines: Types, Advantages and Limitations
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New Research on Autoantibodies
Retail Price: $225.00
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Editors: Claude T. Petrelli
Book Description:
Autoantibodies are a group of antibodies (immune proteins) that mistakenly target and damage specific tissues or organs of the body. One or more autoantibodies may be produced by a person’s immune system when it fails to distinguish between “self” and “non-self" proteins. Usually the immune system is able to discriminate by recognizing foreign substances (“non-self”) and ignoring the body’s own cells ("self"), yet not overreact to non-threatening substances such as foods, dust and pollen, or beneficial microorganisms. It creates antibodies only when it perceives what it has been exposed to as a threat ("non-self"). When the immune system ceases to recognize one or more of the body’s normal constituents as “self”, it may produce autoantibodies that attack its own cells, tissues, and/or organs, causing inflammation and damage. The causes of this inappropriate action are varied and are not well understood, often resulting in a chronic autoimmune disorder. While there is not a direct link, it is thought that many cases of autoantibody production are due to a genetic predisposition combined with an environmental trigger (such as a viral illness or a prolonged exposure to certain toxic chemicals). Some families have been shown to have a high prevalence of autoimmune conditions; however, individual family members may have different autoimmune disorders or may never develop an autoimmune condition. Researchers believe that there may also be a hormonal component to the cause as many of the autoimmune conditions are more common in women of childbearing age. This new book presents leading research from throughout the world.

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Chapter 0 - Autoantibodies Against Coagulation Factors (pp. 1-10)
Authors / Editors: Massimo Franchini, Dino Veneri and Giuseppe Lippi

Chapter 0 - Limitations of Methods for Detection of oLDL-Ab and oLDL (pp. 11-12)
Authors / Editors: F. Tatzber, U. Resch and W. Wonisch

Chapter 0 - An Experimental Autoimmune Kidney Disease Caused by Pathogenic Autoantibodies (pp. 151-172)
Authors / Editors: Arpad Zsigmond Barabas, Chad Douglas Cole, Arpad David Barabas and Rene Lafreniere

Chapter 1 - Macroprolactinemia: A New Cause of Hyperprolactinemia due to Anti-prolactin (PRL) Autoantibodies (pp. 13-59)
Authors / Editors: Naoki Hattori

Chapter 2 - Antibodies to DNA in Systemic Lupus Erythematosus: A Review and Update (pp. 61-86)
Authors / Editors: Antonio La Cava

Chapter 3 - Clinical Significance of Autoantibodies in Systemic Lupus Erythematosus (pp. 87-108)
Authors / Editors: José M. Porcel and Aureli Esquerda

Chapter 4 - Auto-Antibodies Associated with Eye Diseases (pp. 109-130)
Authors / Editors: Márcia Midori Shinzato

Chapter 5 - New Insights Exploring Differences between Antiphospholipid Syndrome and Infections Related Antiphospholipid Antibodies (pp. 131-149)
Authors / Editors: Ricardo Forastiero, Marta Martinuzzo and Gabriela de Larrañaga

Chapter 7 - New Research on Auto-Antibodies (pp. 173-183)
Authors / Editors: Hideo Hara , Takateru Mihara, Kunihiko Asakura, Madoka Ueda, Akihiro Ueda, Mayumi Senda and Tatsuro Mutoh

Chapter 8 - Insights into the Role of Antiendotelial Cell Antibodies in Vasculitis and Connective Tissue Disease (pp. 185-198)
Authors / Editors: Cristina Belizna, Jan Wilhem Cohen Tervaert and Hervé Lévesque

   Binding: Hardcover
   Pub. Date: 2009
   ISBN: 978-1-60456-055-8
   Status: AV
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
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New Research on Autoantibodies