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New Research on Autoantibodies
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Editors: Claude T. Petrelli
Book Description:
Autoantibodies are a group of antibodies (immune proteins) that mistakenly target and damage specific tissues or organs of the body. One or more autoantibodies may be produced by a person’s immune system when it fails to distinguish between “self” and “non-self" proteins. Usually the immune system is able to discriminate by recognizing foreign substances (“non-self”) and ignoring the body’s own cells ("self"), yet not overreact to non-threatening substances such as foods, dust and pollen, or beneficial microorganisms. It creates antibodies only when it perceives what it has been exposed to as a threat ("non-self"). When the immune system ceases to recognize one or more of the body’s normal constituents as “self”, it may produce autoantibodies that attack its own cells, tissues, and/or organs, causing inflammation and damage. The causes of this inappropriate action are varied and are not well understood, often resulting in a chronic autoimmune disorder. While there is not a direct link, it is thought that many cases of autoantibody production are due to a genetic predisposition combined with an environmental trigger (such as a viral illness or a prolonged exposure to certain toxic chemicals). Some families have been shown to have a high prevalence of autoimmune conditions; however, individual family members may have different autoimmune disorders or may never develop an autoimmune condition. Researchers believe that there may also be a hormonal component to the cause as many of the autoimmune conditions are more common in women of childbearing age. This new book presents leading research from throughout the world.

Please click on a chapter below to purchase separately

Chapter 0 - Autoantibodies Against Coagulation Factors (pp. 1-10)
Authors / Editors: Massimo Franchini, Dino Veneri and Giuseppe Lippi

Chapter 0 - Limitations of Methods for Detection of oLDL-Ab and oLDL (pp. 11-12)
Authors / Editors: F. Tatzber, U. Resch and W. Wonisch

Chapter 0 - An Experimental Autoimmune Kidney Disease Caused by Pathogenic Autoantibodies (pp. 151-172)
Authors / Editors: Arpad Zsigmond Barabas, Chad Douglas Cole, Arpad David Barabas and Rene Lafreniere

Chapter 1 - Macroprolactinemia: A New Cause of Hyperprolactinemia due to Anti-prolactin (PRL) Autoantibodies (pp. 13-59)
Authors / Editors: Naoki Hattori

Chapter 2 - Antibodies to DNA in Systemic Lupus Erythematosus: A Review and Update (pp. 61-86)
Authors / Editors: Antonio La Cava

Chapter 3 - Clinical Significance of Autoantibodies in Systemic Lupus Erythematosus (pp. 87-108)
Authors / Editors: José M. Porcel and Aureli Esquerda

Chapter 4 - Auto-Antibodies Associated with Eye Diseases (pp. 109-130)
Authors / Editors: Márcia Midori Shinzato

Chapter 5 - New Insights Exploring Differences between Antiphospholipid Syndrome and Infections Related Antiphospholipid Antibodies (pp. 131-149)
Authors / Editors: Ricardo Forastiero, Marta Martinuzzo and Gabriela de Larrañaga

Chapter 7 - New Research on Auto-Antibodies (pp. 173-183)
Authors / Editors: Hideo Hara , Takateru Mihara, Kunihiko Asakura, Madoka Ueda, Akihiro Ueda, Mayumi Senda and Tatsuro Mutoh

Chapter 8 - Insights into the Role of Antiendotelial Cell Antibodies in Vasculitis and Connective Tissue Disease (pp. 185-198)
Authors / Editors: Cristina Belizna, Jan Wilhem Cohen Tervaert and Hervé Lévesque

   Binding: Hardcover
   Pub. Date: 2009
   ISBN: 978-1-60456-055-8
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
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New Research on Autoantibodies