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Genetic Predisposition to Disease
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Authors: Sara L. Torres and Marta S. Marin 
Book Description:
A genetic predisposition is a genetic effect which influences the phenotype of an organism but which can be modified by the environmental conditions. Genetic testing is able to identify individuals who are genetically predisposed to certain health problems such as cancer or other life altering diseases. This new book discusses the determination of the genetic basis of health problems that will help the precise mechanisms of health problem such as a disease or physical disorder.

Table of Contents:
Preface

1. Genetic Predisposition to Atopic Dermatitis
(Chikako Kiyohara, Department of Preventive Medicine, Graduate School of Medical Sciences, Kyushu University, Keiko Tanaka, Yoshihiro Miyake, Department of Public Health Fukuoka University School of Medicine, Fukuoka, Japan) pp. 1-37

2. Genetic Control of T Cell Immune Tolerance Mechanisms and Susceptibility to Autoimmune Disease
(Lydia Makaroff, Department of Immunology, University of Washington, USA, Michelle Linterman, The John Curtin School of Medical Research, The Australian National University, Canberra, Adrian Liston, Department of Immunology, University of Washington, Seattle, The John Curtin School of Medical Research, The Australian National University, Canberra)pp. 39-71

3. Biological Significance of Human Endogenous Retrovirus (HERVs) and their role in Autoimmunity
(Eva Balada, Josep Ordi-Ros and Miquel Vilardell-Tarrés, Research Unit in Systemic Autoimmune Diseases, Vall D'Hebron Research Institute, Barcelona, Spain)pp. 73-117

4. Mannose-Binding Lectin, A Multifunctional Molecule of the Innate Immune System: Biology, Genetics and Disease Association
(Iara de Messias-Reason and Angelica B.W. Boldt, Molecular and Immunopathology Laboratory, Department of Medical Pathology, Federal University of Paraná, Curitiba, Brazil)pp. 119-174

5. Conserved Extended HLA Haplotype: Disease Association by Genetically Encoded Alteration of the Immune Response
(Judit Laki, Department of Rheumatology, National Health Center, Budapest, Hungary) pp. 175-193

6. Epistasis: Understanding and Evaluating the Phenomenon in Human Genetics Disease Mapping
(Stacey J. Wood, Alison A. Motsinger-Reif, Bioinformatics Research Center, Department of Statistics, North Carolina State University, USA) pp. 195-213

7. Genetic Control of Catalepsy in Mice
(Kulikov Alexander V. and Popova Nina K., Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Russia) pp. 215-236

8. netic Predisposition to Testicular Germ Cell Tumours
(Fiona MA McDonald and Elizabeth A. Rapley, Testicular Cancer Genetics Team, Section of Cancer Genetics, Institute of Cancer Research, UK) pp. 237-255

9. Different Environmental Influences on Aetiology of Atopic Diseases in European Populations as a Basis for Study of Gene-Environment Interactions
(Elena S. Gusareva, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, 3rd Faculty of Medicine, Charles University, Prague, Alexei P. Belozorov, Institute of Dermatology and Venerology, Academy of Medical Sciences of Ukraine, Kharkov, Helena Havelková, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, et al.) pp. 257-270

10. Clinical Investigations of Polymorphism of Insulin-Like Growth Factor I Gene and Retinopathy of Prematurity in Japanese Infants
(Yumiko Tokuhiro, Zenro Kizaki, Department of Pediatrics, Kyoto Prefectural University of Medicine, Kyoto First Red Cross Hospital, Japan, Yasunori Ishihara, Department of Pediatrics, Kyoto Prefectural University of Medicine, Minako Kihara, Kyoto First Red Cross Hospital, Japan, et al.) pp. 271-276

Index

   Binding: Hardcover
   Pub. Date: 2008
   ISBN: 978-1-60456-835-6
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
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