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Advances in Medicine and Biology. Volume 127
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Foldases: Enzymes Catalyzing Protein Folding
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Editors: Natalya K. Nagradova (A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Russia)
Book Description:
A great deal of talent has been called upon over the past decade to try and understand the structure and the function of different types of foldases; as a result, remarkable insights into how these enzymes work has been gained. Recently the main focus of research has begun to shift to unveiling the precise role of these folding catalysts in many different processes in which they are involved inside the cell. It is becoming increasingly clear that the cellular functions of foldases go far beyond accelerating the folding of proteins. This is undoubtedly an area where one can expect significant research efforts in the next few years. The present book summarizes the current state of knowledge as to the structural and functional properties of four major types of foldases listed above. In structuring the material the author has sought to maintain a balance between historical development and current understanding, while also trying to look to the future and anticipate where the field is likely to move.

Table of Contents:
Preface

Chapter 1 - Foldases catalyzing the formation and isomerization of disulfide bonds in proteins; pp. 1-50

Chapter 2 - Peptidyl-prolyl cis/trans isomerases as protein folding catalysts endowed with additional functions; pp. 51-103

Chapter 3 - Foldases integrated into the structure of their cognate proteins as separate domains; pp. 105-153

Chapter 4 - Lipase-specific foldases; pp. 155-178

Chapter 5 - Chaperones as foldases and foldases as chaperones;
pp. 179-222

Index

   Series:
      Molecular Anatomy and Physiology of Proteins - Vladimir N. Uversky (Indiana University of Medicine, USA), Series Editor
   Binding: Hardcover
   Pub. Date: 2008
   Pages: 235 pp.
   ISBN: 978-1-60456-389-4
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
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Foldases: Enzymes Catalyzing Protein Folding