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Advances in Environmental Research. Volume 65
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Future of AV Access: Novel Conduits and Strategies for Improving Maturation (pp. 105-116) $100.00
Authors:  (Dalila White, Philip L. Auyang, and Eric K. Peden)
Renal replacement therapy has evolved since the advent of hemodialysis. Despite
technological improvements and refinement of hemodialysis strategies, a significant
morbidity and mortality is associated with ongoing hemodialysis. A large majority of the
end stage renal patient population depend on hemodialysis and in turn depend on the
function of their hemodialysis access. The National Kidney Foundation has recognized the
significance of arteriovenous (AV) access and survival outcomes targeting AV fistulas as
the access of choice. The success of an AV fistula is complicated by early failure, failure
to mature, and anatomic criteria not met by all patients. In this chapter we explore current
investigations into improving autologous AV fistula maturation and novel access creation
techniques. We analyze early results from phase I and II trials and review multiple research
articles describing strategies to counter the primary causes of fistula failure. We also survey
currently available grafts and novel conduits with the potential to match the efficacy of
autogenous fistula. 

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Future of AV Access: Novel Conduits and Strategies for Improving Maturation (pp. 105-116)