Nova Publishers
My Account Nova Publishers Shopping Cart
HomeBooksSeriesJournalsReference CollectionseBooksInformationSalesImprintsFor Authors
            
  Top » Catalog » Books » Biology » Immunology » My Account  |  Cart Contents  |  Checkout   
Quick Find
  
Use keywords to find the product you are looking for.
Advanced Search
What's New? more
A Crucible of Modern Sport: The Early Development of Football in Sheffield
$85.50
Shopping Cart more
0 items
Information
Shipping & Returns
Privacy Notice
Conditions of Use
Contact Us
Bestsellers
01.Glia and Inflammation in Neurodegenerative Disease
02.Antibiotic Resistance: Causes and Risk Factors, Mechanisms and Alternatives
03.New Developments in Blood Transfusion Research
04.Mast Cells: Roles, Interactions and Disorders
05.Molecular Mechanisms of Tobacco-Induced Diseases
06.Focus on Vitamin E Research
07.Microwave Applications in Pathology
08.Hereditary Immunity: Fundamental Principles and Exploitation in Life Study and Health Care
09.DNA Vaccines: Types, Advantages and Limitations
10.Eosinophils: Structure, Biological Properties and Role in Disease
Notifications more
NotificationsNotify me of updates to Helper T Cells: Types, Functions and New Research
Tell A Friend
 
Tell someone you know about this product.
Helper T Cells: Types, Functions and New Research
Retail Price: $82.00
10% Online Discount
You Pay:

$73.80
Editors: Brando Boudewijn
Book Description:
Helper T Cells: Types, Functions and New Research presents current research in the Tfh cell research field with a special focus on the maintenance of TFH cells and their fate once the immune response has resolved. Whereas early steps of Tfh cell generation have been the subject of intense research in recent years, much less is known about signals controlling Tfh cells in late phases of the germinal center reaction and their differentiation into long-term memory cells. The authors also discuss emerging evidence that CD4+ T cells orchestrate antitumor immunity by providing critical immunological help to B cells, facilitating isotype switching and affinity maturation, and CD8+ T cells, promoting effector and memory differentiation, as well as shaping innate immunity and the tumor microenvironment. While preventing autoimmunity, selective CD4+ T-cell tolerance also compromises immunity to malignant cells that express primarily self-antigens by eliminating CD4+ T-cell help for B-cell, CD8+ T-cell, and innate immune responses. Therefore, the authors suggest that the goal of cancer immunotherapeutics should be increasingly focused on overcoming the CD4+ T-cell tolerance barrier to negate the effects of tolerance-driven immune suppression and maximize antitumor responses. Next, data is presented showing that AIT reduces the expression of CD40L glycoprotein on T CD4+ cells from patients with pollen or Hymenoptera venom allergy when were treated with specific immunotherapy compared to patients not subject to treatment. The function of CD4 T lymphocytes in the development of allergy is discussed, along with the recent results obtained about the impact of AIT on CD40L expression on T helper lymphocytes of patients. (Nova Biomedical)

Table of Contents:
Preface

Chapter 1. Control of T Follicular Helper Cell Function and Fate
(Andreas Hutloff and Annette Lahmann, German Rheumatism Research Center (DRFZ), a Leibniz Institute, Berlin, Germany)

Chapter 2. CD4+ T cells: The Nexus of Tolerance, Autoimmunity and Tumor Immunity
(Tara S. Abraham, Amanda L. Foreman and Adam E. Snook, PhD, Department of Pharmacology and Experimental Therapeutics, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA)

Chapter 3. The Effect of Immunotherapy on CD40L Expression in T Helper Cells from Patients with Allergies
(Josť Miguel Urra, Immunology, Hospital General Universitario de Ciudad Real and Facultad de Medicina Universidad de Castilla La Mancha UCLM, Ciudad Real, Spain)

Chapter 4. Bibliography

Index

   Series:
      Immunology and Immune System Disorders
   Binding: Softcover
   Pub. Date: 2018 - 1st quarter
   ISBN: 978-1-53613-070-6
   Status: AN
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
Special Focus Titles
01.Chaliapin and the Jews: The Question of Chaliapin's Purported Antisemitism
02.The Humanities: Past, Present and Future
03.The Poles: Myths and Reality
04.Child-Rearing: Practices, Attitudes and Cultural Differences
05."A Home Away from Home": A Community of International and South African University Students
06.Palliative Care: Oncology Experience from Hong Kong
07.The Enigma of Autism: Genius, Disorder or Just Different?
08.The Collector Mentality: Modernization of the Hunter-Gatherer
09.Face Processing: Systems, Disorders and Cultural Differences
10.Occurrences, Structure, Biosynthesis, and Health Benefits Based on Their Evidences of Medicinal Phytochemicals in Vegetables and Fruits. Volume 8
11.Crystal Growth: Concepts, Mechanisms and Applications
12.The Economic, Social and Political Impact of Mining on Akyem Abuakwa from the Pre-Colonial Era up to 1943

Nova Science Publishers
© Copyright 2004 - 2017

Helper T Cells: Types, Functions and New Research