Nova Publishers
My Account Nova Publishers Shopping Cart
HomeBooksSeriesJournalsReference CollectionseBooksInformationSalesImprintsFor Authors
            
  Top » Catalog » Books » Biology » Anatomy » My Account  |  Cart Contents  |  Checkout   
Quick Find
  
Use keywords to find the product you are looking for.
Advanced Search
What's New? more
Advances in Medicine and Biology. Volume 127
$250.00
Shopping Cart more
0 items
Information
Shipping & Returns
Privacy Notice
Conditions of Use
Contact Us
Bestsellers
01.Tongue: Anatomy, Kinematics and Diseases
02.Education in Anatomical Sciences
03.Spinal Cord Injuries: Causes, Risk Factors and Management
04.Glycolipids: New Research
05.Pediatric and Adult SinoNasal Disorders
06.Posture: Types, Assessment and Control
07.Soft Tissue: Composition, Mechanisms of Injury and Repair
Notifications more
NotificationsNotify me of updates to Potassium Channels in Health and Disease
Tell A Friend
 
Tell someone you know about this product.
Potassium Channels in Health and Disease
Retail Price: $95.00
10% Online Discount
You Pay:

$85.50
Editors: Hiroaki Kume, M.D., Ph.D. (Kindai University Faculty of Medicine, Ohnohigashi, Osakasayama, Osaka, Japan)
Book Description:
Potassium ion (K+) channels are ubiquitous components and are widely distributed on the surface of the cell membrane in various tissues. There are many types of potassium ion channels (voltage-gated K+ channels, ATP-sensitive K+ channels, Ca2+-activated K+ channels, etc.), and each type of potassium ion channel has its own characteristic features concerning electrophysiology and molecular biology in each potassium ion channel. The potassium ion current across the plasma membrane is considered to have two main physiological functions, one for determining the membrane potential and the other regulating the electrical activity. Membrane hyperpolarization would reduce the excitability of the membrane by shifting the membrane potential away from the threshold for excitation and would inhibit, where it existed, calcium ion (Ca2+) influx through voltage-gated Ca2+ channels by closing the Ca2+ channel. Outward potassium ion currents activated upon depolarization would counteract the depolarizing action of inward currents carried either by sodium ion (Na+) or Ca2+. Therefore, potassium ion channels show the physiological effects in each tissue via membrane potential mediated Ca2+ dynamics (for example, excitation-contraction coupling in muscle). Potassium ion channel activity is also essentially regulated by the intracellular signal transduction pathways, such as receptors’ (G proteins) second messenger molecules processes in the physiological condition. On the other hand, the modification of potassium ion channel activity would be expected to have a significant effect on the excitability of various cells. Therefore, augmentation of outward potassium ion currents may be useful to treat various diseases (asthma, chronic pulmonary obstructive disease, hypertension, diabetes mellitus, glaucoma, arrhythmias, heart failure, epilepsy, etc.). Furthermore, potassium ion channels may be a target protein for the research and development of a therapeutic agent for various diseases concerning the lungs, heart, nerves, eyes, and pancreas. However, there are few books described in detail about potassium ion channels. This book will focus on the characteristics, function and regulation of several types of potassium ion channels, focusing on the role of these channels not only in terms of physical responses, but also in the aforementioned diseases. (Nova Biomedical)


We’ve partnered with Copyright Clearance Center to make it easy for you to request permissions to reuse Nova content.
For more information, click here or click the "Get Permission" button below to link directly to this book on Copyright Clearance Center's website.


Table of Contents:
Preface

Chapter 1. The Potassium Channel in Cardiac Diseases
(Yang Li, Guangzhi Cong, Shaobin Jia, and Xueping Wang, Division of Cardiology, the Chinese PLA General Hospital, Beijing, China, and others)

Chapter 2. The Role of Large-Conductance Calcium-Activated Potassium Channels on Smooth Muscle Cells in Physiological and Pathological Conditions
(Hiroaki Kume, MD, PhD, Department of Respiratory Medicine and Allergology, Kindai University Faculty of Medicine, Ohnohigashi, Osakasayama, Japan)

Chapter 3. ATP-Sensitive Potassium Channels in Uterine Function
(Olga B. Vadzyuk and Dmytro M. Petukhov, Muscle Biochemistry Department, Palladin Institute of Biochemistry, National Academy of Sciences, Kiev, Ukraine, and others)

Index

   Series:
      Human Anatomy and Physiology
   Binding: Softcover
   Pub. Date: 2017
   ISBN: 978-1-53612-927-4
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
Special Focus Titles
01.Looking Upwards: Stars in Ancient and Medieval Cultures
02.Iranians in the Minds of Americans
03.Gleanings in the West of Ireland: Annotated Edition
04.Cystic Tumors of the Pancreas
05.Normalization, Enjoyment and Bodies/Emotions: Argentine Sensibilities
06.Genius, Creativity and Madness
07.The New Age of the Confederacy: Trump and the Surge in National Disunity
08.Social Media: Practices, Uses and Global Impact
09.The Wetlands of India
10.Geomagnetosphere and Coupling Phenomena, Volume I: Solar Wind/IMF Coupling with Geomagnetosphere/Ionosphere
11.Turbochargers and Turbocharging: Advancements, Applications and Research
12.Completion and Unification of Quantum Mechanics with Einstein's GR Ideas, Part II: Unification with GR

Nova Science Publishers
© Copyright 2004 - 2017

Potassium Channels in Health and Disease