Nova Publishers
My Account Nova Publishers Shopping Cart
HomeBooksSeriesJournalsReference CollectionseBooksInformationSalesImprintsFor Authors
            
  Top » Catalog » Books » Biology » Nutrition » Broccoli: Cultivation, Nutritional Properties and Effects on Health Chapters » My Account  |  Cart Contents  |  Checkout   
Quick Find
  
Use keywords to find the product you are looking for.
Advanced Search
What's New? more
Red Sea: Historical Significance, Properties and Economic Importance
$82.00
Shopping Cart more
0 items
Information
Shipping & Returns
Privacy Notice
Conditions of Use
Contact Us
Notifications more
NotificationsNotify me of updates to Broccoli Sprout Supplementation As A Novel Method For Preventing Perinatal Brain Injury (pp. 161-184)
Tell A Friend
 
Tell someone you know about this product.
Broccoli Sprout Supplementation As A Novel Method For Preventing Perinatal Brain Injury (pp. 161-184) $100.00
Authors:  (Jerome Y. Yager, Antoinette T. Nguyen, Jennifer Corrigan, Ashley M.A. Bahry, Ann-Marie Przyslupski, and Edward A. Armstrong, Department of Pediatrics, University of Alberta, Katz Group Centre for Pharmacy and Health Research, Edmonton AB, Canada, and others)
Abstract:
Cerebral palsy is the sine quo non phenotypical outcome measure of perinatal brain
injury. It continues to occur with an incidence of 2-3/1000 live births in term infants. The
incidence increases 10-fold in infants born prematurely, and yet another 10-fold in
developing countries. Risk factors causative for the development of cerebral palsy in
childhood predominantly occur during gestation, prior to the onset of labor and delivery,
whereas only 10-20% of causes occur as a result of a traumatic birth.
Despite these epidemiologic findings, efforts regarding the treatment of perinatal
brain injury are focused on rescue and/or rehabilitation. To address the majority of
causes, however, preventive therapies, provided during gestation, must be developed in
order to treat the ‘at risk’ fetus. Natural health products such as broccoli sprouts and its
active metabolite, sulforaphane, as potent phase-II enzyme inducers, show excellent
promise, given their safety and efficacy profile. In this chapter, we describe a host of preclinical
studies in rodent models of the human risk factors responsible for the majority of
causes of cerebral palsy in children. In this regard, we have utilized Broccoli Sprouts as a
dietary supplement during pregnancy, and shown it to prevent the behavioural and
pathological characteristics typical of perinatal brain damage. Our findings suggest this to
be a viable avenue for further exploration, and a potential safe and efficacious approach
for the prevention of perinatal brain injury and cerebral palsy. 


Available Options:
Version:
This Item Is Currently Unavailable.
Special Focus Titles
01.Looking Upwards: Stars in Ancient and Medieval Cultures
02.Iranians in the Minds of Americans
03.Gleanings in the West of Ireland: Annotated Edition
04.Cystic Tumors of the Pancreas
05.Normalization, Enjoyment and Bodies/Emotions: Argentine Sensibilities
06.Genius, Creativity and Madness
07.The New Age of the Confederacy: Trump and the Surge in National Disunity
08.Social Media: Practices, Uses and Global Impact
09.The Wetlands of India
10.Geomagnetosphere and Coupling Phenomena, Volume I: Solar Wind/IMF Coupling with Geomagnetosphere/Ionosphere
11.Turbochargers and Turbocharging: Advancements, Applications and Research
12.Completion and Unification of Quantum Mechanics with Einstein's GR Ideas, Part II: Unification with GR

Nova Science Publishers
© Copyright 2004 - 2017

Broccoli Sprout Supplementation As A Novel Method For Preventing Perinatal Brain Injury (pp. 161-184)