Authors: (Sabine Montaut, and Patrick Rollin, Laurentian University, Department of Chemistry & Biochemistry, Biomolecular Sciences Programme, Sudbury, ON, Canada, and others)
Abstract: Acting generally as bio-precursors of isothiocyanates (ITCs), glucosinolates (GLs)
are important thiosaccharidic metabolites which occur in all plant families of the order
Brassicales – namely in our daily vegetables. All known GLs (ca 130 characterized
molecules) display a remarkable structural homogeneity invariably based on a β-Dglucopyrano
unit and an O-sulfated anomeric (Z)-thiohydroximate function connected to
a side chain which constitution, depending on plant species, is the sole structural variant.
This chapter will focus on the distribution of GLs in the families of several plant orders
(Brassicales, Malpighiales, Celastrales, Caryophyllales, and Gentianales), the mechanism
of enzymatic degradation of GLs and the goitrogenic activity of this class of natural
products and their enzymatic degradation products.