Nova Publishers
My Account Nova Publishers Shopping Cart
HomeBooksSeriesJournalsReference CollectionseBooksInformationSalesImprintsFor Authors
            
  Top » Catalog » Books » Medicine » Infection » My Account  |  Cart Contents  |  Checkout   
Quick Find
  
Use keywords to find the product you are looking for.
Advanced Search
What's New? more
Medicine Research Summaries (with Biographical Sketches). Volume 15
$175.50
Shopping Cart more
0 items
Information
Shipping & Returns
Privacy Notice
Conditions of Use
Contact Us
Bestsellers
01.Inflammatory Conditions of the Colon
02.A Literature Review of the Practical Application of Bacteriophage Research
03.Bacterial Endocarditis: Etiology, Pathogenesis and Interventions
04.Eye Infections, Blindness and Myopia
05.The First Decade of Safe and Effective HIV Vaccines
06.Cytomegalovirus Infections: Risk Factors, Causes and Management
07.Emerging Geminiviral Diseases and their Management
08.Super-Spreading in Infectious Diseases
09.Helicobacter pylori: Detection Methods, Diseases and Health Implications
10.Development of New Antituberculosis Drugs
Notifications more
NotificationsNotify me of updates to Super-Spreading in Infectious Diseases
Tell A Friend
 
Tell someone you know about this product.
Super-Spreading in Infectious Diseases
Retail Price: $190.00
10% Online Discount
You Pay:

$171.00
Authors: Richard A. Stein, M.D., Ph.D. (Research Scientist, Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA) 
Book Description:
As one of the biological factors that most powerfully impacted history, infectious diseases continue to be a leading cause of global morbidity and mortality. At least two major factors are making infectious diseases assume more important roles than ever before. One of these is the increasing ability of certain microorganisms, normally limited to other species, to cross or jump across the species barrier and become human pathogens. The second factor is our increasing and unprecedented global mobility, which has made traveling between any two remote locations on the planet possible in less than 24 hours. As a result, a local outbreak anywhere in the world becomes a global concern.

A significant challenge that is shared by most (if not all) infectious diseases is our insufficient understanding of the dynamic host-pathogen interaction. In particular, one of the gaps in visualizing our interaction with microorganisms stems from the fact that historically, pathogen transmission in populations was assumed to be homogeneous, with infected individuals having approximately equal opportunities to infect secondary contacts. However, in what became known as “the 20/80 rule”, an increasing number of studies and observations point towards a small number of individuals (20%) that are responsible for most (80%) transmission events in a population. This minority of individuals who infect a disproportionately large number of secondary contacts has become known as “super-spreaders”. The phenomenon of super-spreading lies at the core of understanding the biology of microorganisms and their ability to cause outbreaks, and is instrumental for developing and implementing preventive and therapeutic strategies.

This book proposes to examine super-spreading in infectious diseases. Super-spreading dates back as far as Typhoid Mary, the first documented example, and it was described for most microorganisms, including Mycobacterium tuberculosis, Plasmodium and Schistosoma species, HIV, hepatitis C, influenza virus, Ebola virus, rhinoviruses, Escherichia coli, West Nile virus, and the SARS coronavirus. A thought-provoking find from the SARS pandemic was that in the absence of super-spreading events, most infected individuals caused very few (if any) secondary contacts, but a low number of super-spreaders fueled the global outbreak.

Super-spreading was described in human, animal, and plant hosts, and it exists at the level of the individual as well as at that of the species. One of the common denominators of super-spreading events is that they are virtually always identified only retroactively, as part of epidemiologic investigations. There is, however, a great interest and an acute need in being able to prospectively predict super-spreading, as this would considerably improve the opportunities to prevent, control, and limit outbreaks. A fundamentally important topic in infectious diseases, the study of super-spreading holds key implications for managing epidemics and pandemics, and promises to fill an important gap in microbiology, medicine, public health, agriculture, animal sciences, and biodefense. (Imprint: Nova Biomedical)


Book Reviews

"A delightful and compelling read. Dr. Stein took a relatively complicated topic and made it simple for me as the non infectious disease specialist. I have recommended it to my students and would encourage its use in any medical school curriculum." - Matt T. Rosenberg, M.D., Director of the Mid-Michigan Health Centers, Associate Editor of Urology, International Journal of Clinical Practice MedScape Urology Editorial Board Member

"Super-spreading is as relevant today as it is concerning. Our task is to understand the epidemiology of infectious diseases; specifically, how they are able to move though a population. What Stein has achieved in this detailed, eloquent, and fascinating work, is nothing less than brilliant. He presents easy-to-read, multi-dimensional stories of modern history told through the lens of various infectious diseases. Thoroughly enjoyable on many levels. You will walk away more informed and thoughtful of mankind’s existence and our humble place in the biosphere." - David E. Katz, M.D., M.P.H, FACP, Former Epidemic Intelligence Service Officer, CDC

This book has also been reviewed by the following people:

Stephen A. Berger, M.D., Associate Professor of Medicine, University of Tel Aviv Medical Center, Former Director of Geographic Medicine and Clinical Microbiology, Co-Founder of GIDEON (Global Infectious Diseases and Epidemiology Network). To read the review, click here.

Professor Adrian Streinu-Cercel, M.D., Ph.D., Carol Davila University of Medicine and Pharmacy, National Institute for Infectious Diseases “Prof. Dr. Matei Balș”, Bucharest, Romania. To read the review, click here.



We’ve partnered with Copyright Clearance Center to make it easy for you to request permissions to reuse Nova content.
For more information, click here or click the "Get Permission" button below to link directly to this book on Copyright Clearance Center's website.


Table of Contents:
Preface
pp. vii-ix

Chapter 1. Typhoid Mary and "Mr. N. the Milker"
pp. 1-16

Chapter 2. The Basic Reproduction Number
pp. 17-28

Chapter 3. Super-spreading during the 2002-2003 SARS Pandemic
pp. 29-56

Chapter 4. Super-spreading in Other Infectious Diseases
pp. 57-96

Chapter 5. The Cloud Baby, the Cloud Adult, and the Cloud Healthcare Worker
pp. 97-118

Chapter 6. Super-Spreading in Vector-Borne Diseases
pp. 119-136

Chapter 7. Super-Spreading in Other Species
pp. 137-158

Chapter 8. Before Super-Spreading: Zoonoses and the Species Barrier
pp. 159-192

Index
pp. 193-207

   Series:
      Microbiology Research Advances
   Binding: Hardcover
   Pub. Date: 2015 - 3rd Quarter
   Pages: 7x10 - (NBC-C)
   ISBN: 978-1-63117-295-3
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
Special Focus Titles
01.Essureal Journey: Concepts, Concerns and Considerations for Hysteroscopic Sterilization
02.Feminism: Past, Present and Future Perspectives
03.Accelerating Newborn through Toddler Learning Development
04.Neonatal Intensive Care Units (NICUs): Clinical and Patient Perspectives, Levels of Care and Emerging Challenges
05.Genetic Mistakes: Understanding and Living with Fatty Acid Oxidation Disorders
06.The Impact of Severe Mental Illness on Quality of Life: Challenges for Research and Practices
07.Vukhomba: An Analysis of the Puberty Rites of Passage for Girls among Vatsonga in Relation to Sexuality Education
08.The Challenges and Issues of Tourism Development in China
09.Reconstruction of the Tradition: Tourism and Authentication of Heritage in China
10.Nonlinearity: Problems, Solutions and Applications. Volume 1
11.Adaptive Management: Elements, Applications and Research
12.Natural Fibers: Properties, Mechanical Behavior, Functionalization and Applications

Nova Science Publishers
© Copyright 2004 - 2017

Super-Spreading in Infectious Diseases