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Neuroimmunology Research Perspectives
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Editors: Lilian M. Johansson
Book Description:
Neuroimmunology is a rapidly-growing branch of biomedical science that studies of all aspects of the interactions between the immune system and nervous system. It deals with, among other things, the physiological functioning of the neuroimmune system in states of both health and disease; malfunctions of the neuroimmune system in disorders (autoimmune diseases, hypersensitivities, immune deficiency), the physical, chemical and physiological characteristics of the components of the neuroimmune system in vitro, in situ, and in vivo. Despite the brain's status as an immune privileged site, an extensive bi-directional communication takes place between the nervous and the immune system in both health and disease. Immune cells and neuroimmune molecules such as cytokines, chemokines, and growth factors modulate brain function through multiple signaling pathways throughout the lifespan. Immunological, physiological and psychological stressors engage cytokines and other immune molecules as mediators of interactions with neuroendocrine, neuropeptide, and neurotransmitter systems. For example, brain cytokine levels increase following stress exposure, while treatments designed to alleviate stress reverse this effect. This new book presents leading research from around the globe.

Table of Contents:
Preface (pp. vii-xii)
Expert Commentary (pp. 1-20)

Chapter I - Targeted Immunotherapy in Multiple Sclerosis; (pp. 3-29)
(Guido Cavaletti, Barbara Frigeni, Maura Frigo, Stefania Rota, et al, Dipartimento di Neuroscienze e Tecnologie Biomediche, Univ. di Milano Bicocca, Monza, Italy);

Chapter II - Regulation of Innate Immune Response by Adrenergic and Nicotine Stimulation; (pp. 31-64)
(Hideo Kohka Takahashi, Masahiro Nishibori, Dept. of Pharmacology, Okayama Univ. Grad. Sch. of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan);

Chapter III - Determinant Spreading in Chronic Autoimmune Disorders of the CNS; A New Myth about a Perpetuum Mobile; (pp. 65-101)
(Sandra Amor, Dept. of Immunobiology, Biomedical Primate Research Centre, The Netherlands, Johannes M. van Noort, Dept. of Biosciences, TNO Quality of Life, Leiden, The Netherlands);

Chapter IV - Complement Associated Pathogenic Mechanisms in Myasthenia Gravis; (pp. 103-129)
(Erdem Tuzun, Dept. of Neurology, Div. of Neuro-Oncology, Univ. of PA, Philadelphia, PA, Premkumar Christadoss, Dept. of Microbiology and Immunology, Univ. of Texas Med. Branch, Galeveston, TX);

Chapter V - The Effect of Neuroendocrine System Modulation on Fas-induced Liver Injury; (pp. 131-147)
(Yoichi Chida, Psychobiology Group, Dept. of Epidemiology and Public Health, Univ. College, London, Tetsuya Hiramoto, Dept. of Psychosomatic Medicine, Graduate School of Medical Sciences, Kyushu Univ.)

Chapter VI - Toll-like Receptors: Sensor Molecules for Infection and Tissue Damage in the Nervous System; (pp. 149-168)
(Soojin Lee, Dept. of Microbiology, Chungnam Nat. Univ., Daejeon, Korea, Sung Joong Lee, Program in Molecular and Cellular Neuroscience, DRI, and Dept. of Oral Physiology, Sch. of Denistry, Seoul Nat. Univ. , Seoul, Korea);

Chapter VII - Psychoneuroimmunology of Social Factors in Rodents and Other Animals: An Updated Review; (pp. 169-189)
(Alessandro Bartolomucci, Dept. of Evolutionary and Functional Biology, Univ. of Parma, Parma, Italy);

Chapter VIII - Neuroimmunology Research in Non-human Primates;
(pp. 191-205)
(Bert A. T'hart, Yolanda S. Kap, Dept. of Immunobiology, Biomedical Primate Research Centre, Rijswijk, The Netherlands, Dept. of Immunology, Erasmus Med. Center, Rotterdam, The Netherlands, Sandra Amor and Herbert Brok, Dept. of Immunobiology, Biomedical Primate Research Centre, Rijswijk, The Netherlands);

Chapter IX - The Endocannabinoid System as the Interface Between the Central Nervous System and the Immune System; (pp. 207-229)
(Francisco Molina-Holgado, The Wolfson Centre for Age-Related Diseases, King's College London, London, UK, Angel Arevalo-Martin, Ana Rubio-Araiz, Lab. of Neuroinflammation, Experimental Neurology Unit, Hosp. Nacional de Paraplejicos (SESCAM), Toledo, Spain, Moises Garcia-Arencibia, Dept. de Bioquimica y Biologia Molecular, Fac. de Medicina, Univ. Complutense, Madrid, Spain, et al);

Chapter X - Neuropeptides and Skeletal Muscle Tissue; (pp. 231-251)
(Hanna Gendek-Kubiak, Dept. of Cytophysiology, Histology and Embryology, Med. Univ. of Lodz, Lodz, Poland);

Index (pp. 253-270)

   Binding: Hardcover
   Pub. Date: 2007
   ISBN: 1-60021-532-7
   Status: AV
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
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