Safety of transcranial direct current stimulation (tDCS) in protocols involving human subjects (pp. 285-294)
Authors: (Arun Sundaram, Veronika Stock, Ricardo A. Cruciani and Helena Knotkova)
Abstract: The purpose of this review was to evaluate safety of
Transcranial Direct Current Stimulation (tDCS) in humans.
We have performed a focused search in two major medical
databases, Medline and PubMed, for original articles on
tDCS in humans (healthy subjects and patients with various
diagnoses) published in English. A primary search yielded
141 articles. Fifty-two articles were excluded for the
following reasons: 17 articles were review papers, 26
articles were deemed not related to tDCS, and nine articles
did not provide a complete list of the stimulationparameters.
A total of 89 articles involving tDCS protocols
in human subjects were analyzed in the scope of safety
parameters, with the main focus on the Current Density and
Total Charge. The findings of the review further support the
existing evidence on tDCS safety.
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