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Plasminogen Activator: Genetic Factors, Functions and Clinical Applications $150.00
Editors: Jeremiah M. Rutherford
Book Description:
The Plasminogen Activator System (PAS) is a multifunctional protease system known to possess mitogenic, chemotactic, adhesive and migratory properties. Consequently, it plays an essential role in the process of tumor cell growth and metastasis. Tissue plasminogen activator (tPA) is a member of the serine protease family that plays a pivotal role in the homeostasis of blood coagulation/fibrinolysis and matrix regulation. This book discusses the use of PAS in cancer treatment; its role in chronic kidney disease; the genetic factors, functions, and clinical applications; obesity in adolescents; and the mutual interactions and potential combinatory implications in oncotherapies. (Imprint: Nova Biomedical)

Table of Contents:
Preface

Targeting Plasminogen Activator System in Cancer Treatment
(Ezio Fasoli, Vibha Bansal, Department of Chemistry, University of Puerto Rico at Humacao, Humacao, PR, USA, and others)

Interplay of Plasminogen Activator with the Plasma Kallikrein-Kinin System
(Dhaval Kolte, Jaya Mallela, Zia Shariat-Madar, Department of Medicine, New York Medical College, Valhalla, NY, USA, and others)

Tissue Plasminogen Activator and Chronic Kidney Disease: More than a Simple Protease
(Ling Lin, Kebin Hu, Division of Nephrology, Department of Medicine,
Penn State University College of Medicine, Hershey, Pennsylvania, USA)

Plasminogen Activator Inhibitor-1 in Pediatrics: Genetic Factors, Functions and Clinical Applications
(Ramón Cañete, Miguel Valle, Rosario Martos, María Dolores Cañete, Eva L. van Donkeelar, Pediatric Endocrinology Unit. Hospital Universitario Reina Sofía, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC Maimónides Institute for Biomedical Research in Cordova), Cordova, Spain, and others)

Plasminogen Activator Inhibitor and Obesity in Adolescents
(Deborah Cristina Landi Masquio, Raquel Munhoz da Silveira Campos, Bárbara Dal Molin Netto, Ana R. Dâmaso, Post-Graduate Program of Nutrition, Universidade Federal de São Paulo, São Paulo-SP, Brasil, and others)

Transforming Growth Factor-Beta Regulation of Urokinase Type Plasminogen System: Mutual Interactions and Potential Combinatory Implications in Oncotherapies
(Juan F. Santibanez, Jelena Krstic, Laboratory for Experimental Hematology. Institute for Medical Research (IMI). University of Belgrade, Dr. Subotića, Belgrade, Serbia)

Index

   Series:
      Protein Biochemistry, Synthesis, Structure and Cellular Functions
   Binding: ebook
   Pub. Date: 2014
   Pages: 6x9 - (NBC-R)
   ISBN: 978-1-63117-354-7
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
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