Current Progress in Femtosecond Laser-Assisted Endothelial Keratoplasty (pp. 297-312)
Authors: (Andri K. Riau and Jodhbir S. Mehta, Tissue Engineering and Stem Cell Group, Singapore Eye Research Institute, Singapore, and others)
Abstract: The introduction of femtosecond laser has been a revolution in corneal refractive
surgery. The femtosecond laser is able to deliver precise intrastromal cuts and offer a
wide range of applications in corneal refractive surgery, including endothelial
keratoplasty (EK). Femtosecond lasers offer more consistency and flexibility in cutting
depth than conventional microkeratomes in dissecting donor posterior lamellar disc
(PLD) for EK surgeries. However, there is variability in the smoothness of cut interface
when using femtosecond laser to prepare the donor tissue, which has prevented it from
achieving on-par clinical results with microkeratome-assisted EK. Therefore, many
studies have focused on optimizing the laser settings and refining the technique. In this
chapter, we summarize the current progress in femtosecond laser-assisted EK.
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