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01.Gene Silencing: New Research
02.New Research on DNA Damage
03.Life Span Development in Genetic Disorders: Behavioral and Neurobiological Aspects
04.MicroRNA let-7: Role in Human Diseases and Drug Discovery
05.Myelin Basic Protein
06.New Research on Genomic Instability
07.Developmental Gene Expression Regulation
08.Lecture Notes on Computational Mutation
09.Fragile Sites: New Discoveries and Changing Perspectives
10.Progress in Stem Cell Applications
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New Research on DNA Repair
Retail Price: $265.00
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Editors: Breehn R. Landseer
Book Description:
As a major defense against environmental damage to cells DNA repair is present in all organisms including bacteria, yeast, drosophila, fish, amphibians, rodents and humans. DNA repair is involved in processes that minimize cell killling, mutations, replication errors, persistence of DNA damage and genomic instability. Abnormalities in these processes have been implicated in cancer and aging. This new book presents leading-edge research from around the world in this frontal field.

Please click on a chapter below to purchase separately

Chapter 1 - Chapter I - Molecular Targeting of DNA Repair: A Means to Improve Therapeutic Index (pp. 1-37)
Authors / Editors: (Spencer J. Collis, Clare Hall Laboratories, UK)

Chapter 2 - DNA Repair and Lung Cancer (pp. 39-84)
Authors / Editors: (Chikako Kiyohara, Koichi Takayama and Yoichi Nakanishi, Kyushu Univ., Japan)

Chapter 3 - Comet Assay as a Tool to Evaluate DNA Repair Activity and Inhibition (pp. 85-98)
Authors / Editors: (Delia Cavallo and Cinzia Lucia Ursini, ISPESL National Institute for Occupational Safety and Prevention, Italy)

Chapter 4 - Dietary Compounds that Enhance DNA Repair and their Relevance to Cancer and Aging (pp. 99-113)
Authors / Editors: (Harris Bernstein, Cheray Crowley-Skillicorn and Carol Bernstein et al., Univ. of Arizona, USA)
***Open Access Chapter. Free Download Available***

Chapter 5 - Gene Prophylaxis of Endogenous DNA Damage (pp. 115-166)
Authors / Editors: (Guido Frosina, Istituto Nazionale Ricerca Cancro, Italy)

Chapter 6 - Translesion DNA Synthesis-A Fundamental DNA Damage Tolerance Mechanism (pp. 167-190)
Authors / Editors: (Errol C. Friedberg and Lisa D. McDaniel, Univ. of Texas Southwestern Medical Center at Dallas, USA)

Chapter 7 - Long Term RNA Interference: Toward a Set of Isogeneic Human Deficient Cells in DNA Repair Genes (pp. 191-217)
Authors / Editors: (D.S.F. Biard and J.F. Angulo)

Chapter 8 - Peculiarities of Base Excision Repair in Loach Embryogenesis (pp. 219-249)
Authors / Editors: (Natalia Sharova, Russian Academy of Sciences, Russia)

Chapter 9 - Roles of Plant Transcription Factor IIH Subunit Homologs in Nucleotide Excision Repair and Transcription (pp. 251-272)
Authors / Editors: (Desma M. Grice, Megan J. Osmond and Michael Stewart et al., Deakin Univ., Australia)

Chapter 10 - Repair of Radiation-induced DNA Double-strand Breaks in Human Cells: History, Progress and Controversies (pp. 273-294)
Authors / Editors: (Aurélie Joubert and Nicolas Foray, European Synchrotron Radiation Facility, France)

Chapter 11 - DNA Double-strand Breaks Repair Pathways in the Framework of Chromatin Index (pp. 295-324)
Authors / Editors: (Tom C. Karagiannis and Assam El-Osta, Trescowthick Research Laboratories, Australia)

Chapter 12 - Role of p53 in the Repair of Ionizing Radiation-Induced DNA Damage (pp. 325-373)
Authors / Editors: (David Murray and Razmik Mirzayans, Univ. of Alberta, Canada)

   Binding: Hardcover
   Pub. Date: 2007
   Pages: 7 x 10, 393pp.
   ISBN: 978-1-60021-385-4
   Status: AV
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
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