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01.Gene Silencing: New Research
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New Research on Genomic Instability
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Editors: Eleanor J. Gloscow
Book Description:
Many cancer biologists now believe that genomic instability not only initiates carcinogenesis, but also allows the tumor cell to become metastatic and evade drug toxicity. The loss of stability of the genome is becoming accepted as one of the most important aspects of carcinogenesis. One of the hallmarks of the cancer cell is the inherent instability of its genome. This book presents new research in this exciting field.

Table of Contents:
Preface

Chapter 1. Focal Degeneration of Aged or Injured Myoepithelial Cells and Resultant Auto-Immunoreactions Trigger Genetic Instability and Breast Cancer Invasion; pp. 1-46
(Yan-gao Man, Armed Forces Institute of Pathology, American Registry of Pathology, Washington D.C., USA)

Chapter 2. Chromosomal Instability and Cancer; pp. 47-76
(Dominik Schnerch, Ralph Wäsch, Albert-Ludwigs Univ. Medical Center, Germany)

Chapter 3. Sponteneous and Induced Chromosomal Instability in Patients with Carcinoma of Cervix Uteri; pp. 77-98
(Eva Bozsaky, Ladislava Wsólova and Jozef Kállay, et al., Slovak Academy of Sciences, Slovak Medical Univ, St. Elisabeth’s Oncological Institute, Slovak Republic)

Chapter 4. Tumors: Their Complex Morphologies and Genetic Instabilities; pp. 99-120
(Leon P. Bignold, Institute of Medical and Veterinary Science, Australia)

Chapter 5. Genomic Instability of the APC Gene Found in Glioblastoma (Nives Pecina-Slaus, Vili Beros and Tamara Nikuseva Martic, et al.; pp. 121-137
(School of Medicine Univ. of Zagreb, Croatia, Univ.Hospital “Sisters of Charity”, Croatia)

Chapter 6. Radiation Hormesis and the Control of Genomic Instability; pp. 139-180
(Bobby R. Scott, Lovelace Respiratory Research Institute, USA)

Chapter 7. “Delayed Division Delay” Revealed by Time-lapse Photographic Study: A New Endpoint of Radiation-induced Genomic Instability; pp. 181-206
(Hiroshi Sasaki, Kyushu Univ., Japan)

Chapter 8. How a Cell Defends Itself Against Genomic Instability Caused by Chromium (Nelly Sapojnikova, Tamar Kartvelishvili and Marina Abuladze, et al.; pp. 207-260
(Institute of Physics, Georgia)

Chapter 9. Genotoxic Stress, S Phase Checkpoint and Apoptosis,;
pp. 261-283
(Hideshi Ishii, Jichi Medical School, Tochigi)

Index

   Binding: Hardcover
   Pub. Date: 2007
   ISBN: 1-60021-320-0
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
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