The surgical reinnervation of the transplanted kidney: Is it needed? (pp. 129-132)
Authors: Tamaz J. Shioshvili (Dept. of Urology at the State Medical Academy), Tbilisi, GA
Abstract: As we can see the kidney decentralization, both at the denervation in situ and in
connection with kidney autotransplantation, caused certain functional and morphological
disturbances; their severity and stability was dependent on the decisive degree of whether the
organ surgical reinnervation was performed or not. In this respect, two principal stages may
be singled out in the postoperative period, 2 months before and after the operation.
In the first stage the experimental results in all test-groups were mainly of the same kind.
During this period a 15-20% decrease of vascularization, filtration, secretion, reabsorption,
excretion and renographic index on both denervated and autotransplanted kidneys was
observed. From a morphological point of view blood stasis, lymphoid infiltration and various
degrees of dystrophy were revealed in the parenchyma. In the nephron proximal and distal
segments dilation of endoplasmatic net cisterns, mitochondria swelling with cristas
destruction and vacuolization were observed.
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