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Neuronal Calcium Sensor Proteins
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Editors: Pavel P. Philippov (M.V. Lomonosov Moscow State University, Russia) and Karl-Wilhelm Koch (University of Oldenburg, Germany)
Book Description:
Calcium signalling is an astonishing example how a simple cation can trigger and regulate an enormous variety of cellular and physiological responses. Ca2+-signalling routes very often involve Ca2+-binding proteins that sense changes in intracellular [Ca2+] and trigger cellular responses by regulating specific targets. One fascinating group among these Ca2+-sensors are the neuronal calcium sensor (NCS) proteins, named for their localization in neuronal tissue (although there are reports of their expression in nonneuronal tissues as well). While recent excellent reviews have covered key aspects of this protein group, the field expanded in recent years making it more and more difficult to represent every facet of this ongoing research endeavor. This book is intended to represent properties of NCS proteins.

Table of Contents:
Preface

Part I: NCS-1 (Frequenin)

1.Frequenin: a highly conserved protein with a conserved funtion?; pp, 3-17
(M.C. Stockebrand and O. Pongs.)

2. Sensing the difference: Neuronal calcium sensor-1 and its involvement in vesicle biogenesis, trafficking and fusion; pp, 19-43
(E. Fdez and S. Hilfiker).

3. NCS-1 as a regulator of Kv4 K+-channels; pp, 45-64
(T.Y. Namamura et al.)

Part II: Hippocalcin, Neurocalcin and VILIPs

4. Hippocalcin V a multifunctional modulator in the hippocampus.; pp, 67-81
(M. Kobayashi and K. Takamatsu)

5. Hippocalcin in the regulation of calcium induced neuronal degeneration; pp, 83-89
(D. Lindholm et al).

6. Constitution and operationional principles of the retinal and odorant-linked neurocalcin -dependent Ca2+-modulated ROS-GC transduction machinery; pp, 91-113
(T. Duda et al.)

7. Structure, function and expression of members of the VILIP (visinin-like proteins) subfamily of neuronal Ca2+-sensor proteins.; pp, 115-135
(M. Brackmann et al)

Part III: Recoverin

8. Recoverin: a calcium-dependent regulator of the visual transduction; pp, 139-151
(P.P. Philippov)

9. Recoverin shapes the photoresponse of retinal rods; pp, 153-180
(R.A. Bush and C.L. Makino)

10.The role of recoverin in autoimmunity; pp, 181-199
(G. Adamus)

Part IV: GCAPs

11. Calcium sensitivity of photoreceptor guanylyl cyclase (RetGC) and congenital photoreceptor degeneration: Modeling in vitro and in vivo; pp, 203-219
(A.M. Dizhoor et al.)

12. Guanylyl cyclase-activating protiens (GCAPs); pp, 221-228
(W. Gorczyca.)

13. Different biochemical properties of guanylate cyclase-activating proteins allow fine tuning of phototransduction.; pp, 229-241
(K.-W. Koch.)

Part V: KChIPs

14. Dream/KchIP/ Calsenilin: a multifunctional player in health and disease; pp, 245-270
(H.-Y. M. Cheng and J.M. Penninger.)

15. A role for Calsenilin in multiple aspectes of neuronal function; pp, 271-284
(W. Wasco and J.D. Buxbaum.)

16. KChIPs as integral K+ channel subunits; pp, 285-297
(K.J. Rhodes and R.H. Scannevin).

Part VI:CaBP

17. Caldendrin- a neuronal calcium binding protein involved in synaptro-dendritic Ca2+ signaling; pp, 301-313
(M.R. Kreutz et al.)

Part VII: Biophysical and chemical approaches to understand NCS protein function

18. Molecular structure and target recognition of neuronal calcium sensor proteins; pp, 317-329
(J.B. Ames and M. Ikura.)

19. The use of physical methods in studies of neuronal calcium sensor proteins; pp, 331-349
(E.A. Permyakov.)

20. In vitro acylation of neurocalcin, exploration of membrane binding properties using surface plasmon resonance; pp, 351-370
(D. Ladant et al.)

Index

   Series:
      Molecular Anatomy and Physiology of Proteins - Vladimir N. Uversky (Indiana University of Medicine, USA), Series Editor
   Binding: Hardback
   Pub. Date: 2006
   ISBN: 1-59454-978-8
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
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