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01.Pharmacological Activity-Based Quality Control of Chinese Herbs
02.Anticancer Drugs: Design, Delivery and Pharmacology
03.Research Progress on Epinephrine
04.Coumarin Anticoagulant Research Progress
05.Amphetamines: Neurobiological Mechanisms, Pharmacology and Effects
06.Biopharmaceutics and Drug Hypersensitivity
07.Cox-2 Inhibitor Research
08.Curcumin: Biosynthesis, Medicinal Uses and Health Benefits
09.Drugs: Approval and Evaluation, Delivery and Control
10.Chondroitin Sulfate: Structure, Uses and Health Implications
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Cox-2 Inhibitor Research
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Editors: Maynard J. Howardell
Book Description:
COX-2 Inhibitors are newly developed drugs for inflammation that selectively block the COX-2 enzyme. Blocking this enzyme impedes the production of the chemical messengers (prostaglandins) that cause the pain and swelling of arthritis inflammation. Cox-2 inhibitors are a new class of nonsteroidal anti-inflammatory drugs (NSAIDS). Because they selectively block the Cox-2 enzyme and not the Cox-1 enzyme, these drugs are uniquely different from traditional NSAIDS. This new book explores new research in this field.

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Table of Contents:

Chapter 1. Cyclooxygenase-2 Inhibitor and Gastric Cancer, pp. 1-83
(Yumin Li, Raaj K Praseedom, and Andrew Butler et al., University of Cambridge, UK).

Chapter 2. Prevention and Chemoprevention of Gastric Cancer: Dietary Habits, Helicobacter pylori and COX-2 Inhibitors, pp. 85-114
(Gerardo Nardone and Alba Rocco, University ”Federico II, Italy).

Chapter 3. Cyclooxygenases in Cancer, pp. 115-143
(Daniela Fodera, and Nadia Lampiasi, Instituto di Biomedicina e Immunologia Molecolare “Alberto Monroy”, Italy and Antonella Cusimano et al., Universita di Palermo, Italy).

Chapter 4. Nephrotoxicity of Nonsteroidal Anti-Inflammatory Drugs: Focus on Selective Cyclooxygenase-2 (COX-2) Inhibitors, pp. 145-180
(Steven G. Coca and Mark A. Perazella, Yale University School of Medicine, CT).

Chapter 5. Are COX-2 Inhibitors Active on Intracellular Oxidative Processes? A Study on In Vitro and Cellular Models, pp. 181-207
(Ange Mouithys-Mickalad, Ginette Deby-Dupont, and Carol Deby et al., Institute of Chemistry, Belgium).

Chapter 6. Theoretical Mechanism Studies on Dual Inhibition of Human Cyclooxygenase-2 and 5-Lipoxygenase by Diaryl-Pyrrolizine Derivatives, pp. 209-235
(R. Pouplana, C. Perez, and J. Ruiz, Universitat de Barcelona, Spain).


   Binding: Hardcover
   Pub. Date: 2006
   ISBN: 978-1-59454-994-6
   Status: AV
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
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02.Breast Surgery: Indications and Techniques
03.Cursed? Biologic and Cultural Aspects of the Menstrual Cycle and Menstruation
04.The Uses of Cocoa and Cupuaçu Byproducts in Industry, Health, and Gastronomy
05.Agriculture, Food, and Food Security: Some Contemporary Global Issues
06.Fungicides: Perspectives, Resistance Management and Risk Assessment
07.Current Developments in Alexithymia - A Cognitive and Affective Deficit
08.Political Concerns and Literary Topoi in French Grand Opera
09.Abdul Aziz Said: The Mualim, The Inspiration
10.Teachers and Teaching: Global Practices, Challenges, and Prospects
11.A Comprehensive Investigation on Executive-Employee Pay Gap of Chinese Enterprises: Antecedents and Consequences
12.American Alligators: Habitats, Behaviors, and Threats

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Cox-2 Inhibitor Research