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Organism Mutation Stability and Cancer (pp. 135-146) $100.00
Authors:  (Edward A. Rietman, J. Tyson McDonald, Lynn Hlatky)
We start with observational evidence to hypothesize that plants are more stable with
respect to an energy threshold required for mutation than animals are. These observations
include ploidy stability in plants, resulting in the fact that plants infrequently get cancer,
and mutation hotspots, the existence of which imply some reproducible mechanism for
mutation. We propose an experiment involving Saccharomyces cerevisiae as a model
animal and Chlamdomonas reinhardtii as a model plant to evaluate our hypothesis. We
further speculate that if we measure the genomic stability of a huge number of species of
plants and animals, we would find a bimodal distribution not unlike those observed for
nonthermal equilibrium states of bipartite systems. 

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Organism Mutation Stability and Cancer (pp. 135-146)