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Histones: Class, Structure and Function
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Editors: Chang-Hui Shen (City University of New York, NY, USA)
Book Description:
Histones are DNA-binding proteins that help in the packaging of DNA to fit into the cell nucleus in a hierarchy of organization. During the packaging and unfolding process, histones are involved in crucial biological activities at the molecular level. This book presents research in the study of histone class, structure and function, including the roles of linker histones in chromatin structure, the post-translational modifications of histones and the importance of chromatin structure and epigenetics in gene regulation and carcinogenesis. (Imprint: Nova)

Table of Contents:
Preface pp. i-xi

Chapter 1. The functionally discrete biological roles of the H1 linker histone subtypes
(Thomae G. Sourlingas, Institute of Biology, Laboratory of Nuclear Proteins and Chromatin Function National Centre for Scientific Research- Demokritos
(Aghia Paraskevi, Attiki, Greece) pp.

Chapter 2. Linker histones and chromatin structure
(Chang-Hui Shen, College of Staten Island, City University of New York
Staten Island, New York, USA; The Graduate Center, City University of New York) pp. 35-58

Chapter 3. The linker histone and chromatin of yeast Saccharomyces cerevisiae
(George Miloshev and Milena Georgieva, Laboratory of Yeast Molecular Genetics, Institute of Molecular Biology, Bulgarian Academy of Sciences, Acad. G. Bonchev 21, Sofia, Bulgaria) pp. 59-76

Chapter 4. Histones in metaphase chromosomes
Susumu Uchiyama and Kiichi Fukui
(Department of Biotechnology, Graduate School of Engineering
Osaka University, Osaka, Japan) pp. 77-88

Chapter 5. Histone modifications and gene activation
(Roshini Nilupama Wimalarathna and Chang-Hui Shen, College of Staten Island, City University of New York, Staten Island, New York, USA)pp. 89-108

Chapter 6. Histone modifiers in cereals
(Aliki Kapazoglou, Dimitra Papaefthimiou1 and Athanasios Tsaftaris
(Institute of Agrobiotechnology, CERTH, Thermi-Thessaloniki, Greece
and others)pp. 109-136

Chapter 7. Histone Phosphorylation and the cell division cycle
(Geoffrey Woodard, Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA)pp. 137-152

Chapter 8. Basic parameters for plant nuclei and 3D localization of histone modification
(Toshiyuki Wako(Division of Plant Sciences, National Institute of Agrobiological Sciences, Tsukuba, Japan and Kiichi Fukui, Department of Biotechnology, Graduate School of Engineering Osaka University, Osaka, Japan)pp. 153-162

Chapter 9. Histone modification by non-enzymatic glycation and preventive strategies
(Gilbert A. Boissonneault, Division of Physician Assistant Studies, College of Health Sciences, University of Kentucky, Lexington, KY, USA)pp. 163-184

Chapter 10. The role of chromatin in inducible gene regulation in the immune system
(Lucy D. Apps and Adele F. Holloway, Menzies Research Institute Tasmania, University of Tasmania, Australia)pp. 185-200

Chapter 11. The chromatin structure of ribosomal DNA
(Benoît Leblanc, Département de Biologie, Faculté des Sciences
Université de Sherbrooke, Quebec, Canada)pp. 201-224

Chapter 12. The Epigenome and its Therapeutic Potential in Breast Cancer
(Virginia A. Spencer, Life Technologies, Cell Culture Essentials, Frederick, Maryland, USA and Jimmie E. Fata, Department of Biology, College of Staten Island, City University of New York, New York, USA)pp. 225-244

Index pp. 245-256

      Protein Biochemistry, Synthesis, Structure and Cellular Functions
   Binding: Hardcover
   Pub. Date: 2012-September
   Pages: 267, 7 x 10 (NBC - C)
   ISBN: 978-1-62100-274-1
   Status: AV
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
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Histones: Class, Structure and Function