Nova Publishers
My Account Nova Publishers Shopping Cart
HomeBooksSeriesJournalsReference CollectionseBooksInformationSalesImprintsFor Authors
  Top » Catalog » Books » Medicine » Cancer » Breast Cancer: Causes, Diagnosis and Treatment Chapters » My Account  |  Cart Contents  |  Checkout   
Quick Find
Use keywords to find the product you are looking for.
Advanced Search
What's New? more
Advances in Medicine and Biology. Volume 129
Shopping Cart more
0 items
Shipping & Returns
Privacy Notice
Conditions of Use
Contact Us
Notifications more
NotificationsNotify me of updates to Breast Cancer and Autophagy, pp. 53-88
Tell A Friend
Tell someone you know about this product.
Breast Cancer and Autophagy, pp. 53-88 $0.00
Authors:  L.J. Armstrong, S.M. Gorski, The Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC, Canada and others
Stress on a cellular level can have detrimental effects on an organism
and has been implicated in many different diseases, including cancer.
Breast cancer, one of the most prevalent forms of the disease, is often
initiated by abnormal cellular mechanisms and damage to DNA brought
about by different types of cellular stress. One method of minimizing
damage caused by stress is a process that occurs within the cell known as
autophagy. Autophagy is a catabolic process in which old and damaged
components of the cell are degraded into their elemental forms and
recycled in order to synthesize additional proteins and energy. Recently a
gene involved in the regulation of autophagy was found to be altered in
breast cancer cells, leading researchers to hypothesize that autophagy
may play a pivotal role in the disease; however the definite role that
autophagy plays in breast cancer is still unclear. Some evidence suggests
that autophagy acts as a tumour suppressor and should be stimulated to
decrease the incidence of cancer in breast cells. Other evidence indicates
that autophagy’s survival effects may actually help breast cancer cells
persist and contribute to chemotherapy resistance in the body. With
increasing experimental evidence supporting each claim, it may be that
the role of autophagy varies depending on the particular type of tumour
and the stage of disease progression. Establishing an accurate link
between autophagy and breast cancer is therefore a very important
objective that could eventually lead to significant therapeutic

Available Options:

  Open Access item.
  Click below PDF icon for free download.


This is an Open Access item. Click above PDF icon for free download.
Special Focus Titles
01.Multicultural and Citizenship Awareness through Language: Cross Thematic Practices in Language Pedagogy
02.The Brainstem and Behavior
03.Sustainable Development: The Context of Use of Indigenous Plants for Local Economic Growth
04.Cancer versus Nutraceuticals
05.Fundamentals of Fuel Injection and Emission in Two-Stroke Engines
06.Free to Love: Schema Therapy for Christians
07.Textiles: Advances in Research and Applications
08.Cheese Production, Consumption and Health Benefits
09.Education in Lesotho: Prospects and Challenges
10.Work-Life Balance in the 21st Century: Perspectives, Practices, and Challenges
11.Electrical Measurements: Introduction, Concepts and Applications
12.Potassium Channels in Health and Disease

Nova Science Publishers
© Copyright 2004 - 2018

Breast Cancer and Autophagy, pp. 53-88