Nova Publishers
My Account Nova Publishers Shopping Cart
HomeBooksSeriesJournalsReference CollectionseBooksInformationSalesImprintsFor Authors
  Top » Catalog » Books » Medicine » Cancer » Breast Cancer: Causes, Diagnosis and Treatment Chapters » My Account  |  Cart Contents  |  Checkout   
Quick Find
Use keywords to find the product you are looking for.
Advanced Search
What's New? more
Emerging Materials for Environment Protection and Renewable Energy
Shopping Cart more
0 items
Shipping & Returns
Privacy Notice
Conditions of Use
Contact Us
Notifications more
NotificationsNotify me of updates to Breast Cancer and Autophagy, pp. 53-88
Tell A Friend
Tell someone you know about this product.
Breast Cancer and Autophagy, pp. 53-88 $0.00
Authors:  L.J. Armstrong, S.M. Gorski, The Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC, Canada and others
Stress on a cellular level can have detrimental effects on an organism
and has been implicated in many different diseases, including cancer.
Breast cancer, one of the most prevalent forms of the disease, is often
initiated by abnormal cellular mechanisms and damage to DNA brought
about by different types of cellular stress. One method of minimizing
damage caused by stress is a process that occurs within the cell known as
autophagy. Autophagy is a catabolic process in which old and damaged
components of the cell are degraded into their elemental forms and
recycled in order to synthesize additional proteins and energy. Recently a
gene involved in the regulation of autophagy was found to be altered in
breast cancer cells, leading researchers to hypothesize that autophagy
may play a pivotal role in the disease; however the definite role that
autophagy plays in breast cancer is still unclear. Some evidence suggests
that autophagy acts as a tumour suppressor and should be stimulated to
decrease the incidence of cancer in breast cells. Other evidence indicates
that autophagy’s survival effects may actually help breast cancer cells
persist and contribute to chemotherapy resistance in the body. With
increasing experimental evidence supporting each claim, it may be that
the role of autophagy varies depending on the particular type of tumour
and the stage of disease progression. Establishing an accurate link
between autophagy and breast cancer is therefore a very important
objective that could eventually lead to significant therapeutic

Available Options:

  Open Access item.
  Click below PDF icon for free download.


This is an Open Access item. Click above PDF icon for free download.
Special Focus Titles
01.Heart Failure: What a Non-Heart Failure Specialist Needs to Know
02.Bottle-Feeding: Perceptions, Practices, and Health Outcomes
03.Between Success and Failure: Assessment of Aspirations and Risk (CD Included)
04.Understanding Left and Right: An Illustrated Guide to the Political Divide
05.Phytoremediation: Methods, Management and Assessment
06.“Waste-to-Profit” (W-t-P): Value added Products to Generate Wealth for a Sustainable Economy. Volume 1
07.The Impact and Implications of Crisis: A Comprehensive Approach Combining Elements of Health and Society
08.When "We" Are Stressed: A Dyadic Approach to Coping with Stressful Events
09.The Man Brand: Why Public Campaigns Hide Half of Intimate Partner Violence
10.The Life of Abraham Lincoln: Drawn from Original Sources and Containing Many Speeches, Letters and Telegrams Hitherto Unpublished. Volume One
11.Life of Charles Dickens
12.The Inventions and Discoveries of the World’s Most Famous Scientists

Nova Science Publishers
© Copyright 2004 - 2018

Breast Cancer and Autophagy, pp. 53-88