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Cytoskeleton: Cell Movement, Cytokinesis and Organelles Organization $129.00
Editors: Sébastien Lansing and Tristan Rousseau
Book Description:
In this book, the authors review the effects of uPAR on the actin, intermediate filaments and microtubules that constitute the cell cytoskeleton, and the mechanisms used by uPAR to modulate intracellular signalling and temporally fine tune cytoskeletal dynamics. The effects of cytoskeletal components of uPAR expression and cellular distribution are examined as well. In addition, Duchenne Muscular Dystrophy (DMD) is an inherited disorder characterized by progressive muscular degeneration and cognitive impairment due to mutations in the DMD gene. Elucidation of the molecular basis for this illness has determined that cytoskeleton and the product of the DMD gene called dystrophin work in a coordinated way to maintain fibre muscle integrity. The authors describe the scientific path that allows elucidation of the molecular basis of DMD. Furthermore, cell motility is central to many aspects of cell, tissue, and organ function in both health and disease. Some of the more popular published experimental approaches to study cell motility are discussed. Also examined are the IQGAP family of proteins, which are now known to act at the interface between cellular signalling pathways and the actin cytoskeleton.

Table of Contents:
Preface

Follow the Leader: When the Urokinase Receptor Coordinates Cell Adhesion, Motility and Proliferation with Cytoskeleton Organization;pp. 1-36
(Marco Archinti, Gabriele Eden, Ronan Murphy, and Bernard Degryse, Institute for Research in Biomedicine, Parc Cientific de Barcelona, Baldiri Reixac, Barcelona, Spain, and others)

LIMK 1, The Key Enzyme of Actin Remodeling Bridges Spatial Organization of Nucleus and Neural Transmission: From Heterochromatin Via Non-Coding RNAs to Complex Behavior;pp. 37-68
(Anna V. Medvedeva, Alexander V. Zhuravlev, Elena V. Savvateeva-Popova, Pavlov Institute of Physiology, Russian Academy of Sciences, Laboratory of Neurogenetics, St. Petersburg, Russia)

Common Tasks of Cytoskeleton and Dystrophin in Muscular and Neurological Functions: Perspectives in Gene Therapy;pp. 69-100
(Joel Cerna Cortés, Dominique Mornet, Doris Cerecedo, Francisco García-Sierra, Janet Hummel, Eliud Alfredo García Montalvo, Olga Lidia Valenzuela Limón, Valery Melnikov, Sergio Adrián Montero Cruz, Juan Alberto Osuna Castro, Alejandra Mancilla, Rafael Rodríguez-Muñoz, Bulmaro Cisneros, Facultad de Medicina, Universidad de Colima, Colima, México, and others)

Measuring Reciprocal Regulation of Mesenchymal Stem Cell and Tumor Cell Motility in Two and Three Dimensions In Vitro;pp. 101-126
(Vilma Sardão, Teresa Rose-Hellekant, Ed Perkins, Amy Greene, Jon Holy, Department of Zoology, Center for Neurosciences and Cellular Biology, University of Coimbra, Coimbra, Portugal)

Centriole Duplication or DNA Replication: What Starts Earlier?;pp. 127-137
(R. E. Uzbekov, I. B. Alieva, Laboratory of Cell Biology and Electron Microscopy, Faculty of Medicine, François Rabelais University, Tours, France, and others)

The Myosin Light Chain-IQGAP Interaction: What is its Function?;pp. 139-147
(David J. Timson, School of Biological Sciences, Queen's University Belfast, Medical Biology Centre, Belfast, UK)

Migrating Plant Cell: F-Actin Asymmetry Directed by Phosphoinositide Signaling;pp. 149-159
(Koji Mikami, Faculty of Fisheries Sciences, Hokkaido University, Hakodate, Japan)

Membrane Microdomains and Neural Impulse Propagation: Field Effects in Cytoskeleton Corrals;pp. 161-177
(Ron Wallace, Department of Anthropology, University of Central Florida, Orlando, Florida)*

Scaffolding Proteins that Regulate the Actin Cytoskeleton in Cell Movement;pp. 179-250
(S.J. Annesley, P.R. Fisher, Microbiology Dept., La Trobe University, Melbourne, Australia)*

Index

   Series:
      Cell Biology Research Progress
   Binding: ebook
   Pub. Date: 2010
   Pages: 7 x 10, 249 pp.
   ISBN: 978-1-61122-941-7
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
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Cytoskeleton: Cell Movement, Cytokinesis and Organelles Organization