Nova Publishers
My Account Nova Publishers Shopping Cart
HomeBooksSeriesJournalsReference CollectionseBooksInformationSalesImprintsFor Authors
  Top » Catalog » Books » Materials Science » Advances in Condensed Matter and Materials Research, Volume 7 Chapters » My Account  |  Cart Contents  |  Checkout   
Quick Find
Use keywords to find the product you are looking for.
Advanced Search
What's New? more
Novel Systems and Applications in Clean Energy
Shopping Cart more
0 items
Shipping & Returns
Privacy Notice
Conditions of Use
Contact Us
Notifications more
NotificationsNotify me of updates to Biodegradable Hydrogels as Drug Delivery Systems for Tissue Engineering Applications pp. 459-474
Tell A Friend
Tell someone you know about this product.
Biodegradable Hydrogels as Drug Delivery Systems for Tissue Engineering Applications pp. 459-474 $100.00
Authors:  Kacey G. Marra, Alicia J. DeFail, Division of Plastic and Reconstructive Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA, and others
Tissue engineering is a potential therapeutic strategy which combines scaffolds, cells, and/or growth factors that provide a suitable environment to direct the growth of new, healthy tissue. Scaffolds that are biodegradable, biocompatible, mechanically support tissue growth, and can be shaped to fill an irregularly shaped defect are ideal. Polymeric poly(lactic-co-glycolic acid) (PLGA) biomaterials are among the most widely studied tissue-engineered scaffolds. However, polymeric hydrogels, such as poly(ethylene glycol) (PEG) are also being examined as drug delivery scaffolds. Delivery of drugs or growth factors from these scaffolds is desirable to enhance tissue regeneration. The delivery of drugs or growth factors can be controlled by various parameters such as drug loading, polymer composition, and processing techniques. Drugs can also be encapsulated in microspheres or nanospheres for controlled delivery. Other methods of delivery include adsorption of drugs or growth factors to the surface prior to implantation or incorporation during the scaffold fabrication process. The incorporation of microspheres within PLGA scaffolds, fibrin scaffolds, gelatin scaffolds, and poly(ethylene glycol)-based hydrogels is also an option. This chapter describes several of these approaches that results in a controlled, localized release of drugs from the biomaterials. Clinical applications that will be discussed include bone regeneration, breast cancer adjuvant therapies, and nerve regeneration. 

Available Options:
This Item Is Currently Unavailable.
Special Focus Titles
01.Peter Singerís Ethics: A Critical Appraisal
02.Sexism: Past, Present and Future Perspectives
03.Body and Politics: Elite Disability Sport in China
04.Childhood and Adolescence: Tribute to Emanuel Chigier, 1928-2017
05.Renal Replacement Therapy: Controversies and Future Trends
06.Food-Drug Interactions: Pharmacokinetics, Prevention and Potential Side Effects
07.Terrorism and Violence in Islamic History and Theological Responses to the Arguments of Terrorists
08.International Event Management: Bridging the Gap between Theory and Practice
09.The Sino-Indian Border War and the Foreign Policies of China and India (1950-1965)
10.Tsunamis: Detection, Risk Assessment and Crisis Management
11.Sediment Watch: Monitoring, Ecological Risk Assessment and Environmental Management
12.Self-Regulated Learners: Strategies, Performance, and Individual Differences

Nova Science Publishers
© Copyright 2004 - 2018

Biodegradable Hydrogels as Drug Delivery Systems for Tissue Engineering Applications pp. 459-474