Nova Publishers
My Account Nova Publishers Shopping Cart
HomeBooksSeriesJournalsReference CollectionseBooksInformationSalesImprintsFor Authors
            
  Top » Catalog » Journals » Journal of Stem Cells Volumes / Issues » Journal of Stem Cells, Volume 4, Issue 4 Articles » My Account  |  Cart Contents  |  Checkout   
Quick Find
  
Use keywords to find the product you are looking for.
Advanced Search
What's New? more
Advances in Nanotechnology. Volume 21
$250.00
Shopping Cart more
0 items
Information
Shipping & Returns
Privacy Notice
Conditions of Use
Contact Us
Notifications more
NotificationsNotify me of updates to Hyaluronan Stimulates Mobilization of Mature Hematopoietic Cells but Not Hematopoietic Progenitors pp. 191-202
Tell A Friend
 
Tell someone you know about this product.
Hyaluronan Stimulates Mobilization of Mature Hematopoietic Cells but Not Hematopoietic Progenitors pp. 191-202 $0.00
Authors:  Ingrid Schraufstatter, Naira Serobyan, Richard DiScipio, Natalia Feofanova, Irina Orlovskaya and Sophia Khaldoyanidi
Abstract:
Mobilization of hematopoietic stem/progenitor cells (HSPCs) is currently a routine clinical procedure that enables the harvesting of HSPCs from peripheral blood and their further use for transplantation and tissue regeneration. Despite of the recent progress in HSPC mobilization strategies, it is generally agreed that further improvement of mobilization protocols is needed to achieve a better quantity and quality of harvested HSPC in a higher percentage of donors (Pelus 2008).
The protocols for HSPC mobilization are based on understanding the molecular mechanisms that regulate homing of these cells into the bone marrow and their retention within the niche. In particular, several chemokines, cytokines, growth factors, their receptors, adhesion molecules as well as hormones and proteases have been identified as contributors to the complex network that regulates migration of HSPCs (Lapidot and Petit 2002; Cottler-Fox, Lapidot et al. 2003; Levesque and Winkler 2008; Pelus 2008; Schulz, von Andrian et al. 2009). Apparently, agents used for HSPC mobilization interrupt these pathways and enable HSPC to detach from the niche, migrate through the matrix, egress from the bone marrow and enter the circulation. 


Available Options:
Version:
This Item Is Currently Unavailable.
Special Focus Titles
01.Looking Upwards: Stars in Ancient and Medieval Cultures
02.Iranians in the Minds of Americans
03.Gleanings in the West of Ireland: Annotated Edition
04.Cystic Tumors of the Pancreas
05.Normalization, Enjoyment and Bodies/Emotions: Argentine Sensibilities
06.Genius, Creativity and Madness
07.The New Age of the Confederacy: Trump and the Surge in National Disunity
08.Social Media: Practices, Uses and Global Impact
09.The Wetlands of India
10.Geomagnetosphere and Coupling Phenomena, Volume I: Solar Wind/IMF Coupling with Geomagnetosphere/Ionosphere
11.Turbochargers and Turbocharging: Advancements, Applications and Research
12.Completion and Unification of Quantum Mechanics with Einstein's GR Ideas, Part II: Unification with GR

Nova Science Publishers
© Copyright 2004 - 2017

Hyaluronan Stimulates Mobilization of Mature Hematopoietic Cells but Not Hematopoietic Progenitors pp. 191-202