Nova Publishers
My Account Nova Publishers Shopping Cart
HomeBooksSeriesJournalsReference CollectionseBooksInformationSalesImprintsFor Authors
            
  Top » Catalog » Journals » Journal of Stem Cells Volumes / Issues » Journal of Stem Cells, Volume 4, Issue 4 Articles » My Account  |  Cart Contents  |  Checkout   
Quick Find
  
Use keywords to find the product you are looking for.
Advanced Search
What's New? more
Hydrometallurgy: Applications, Technology and Research
$82.00
Shopping Cart more
0 items
Information
Shipping & Returns
Privacy Notice
Conditions of Use
Contact Us
Notifications more
NotificationsNotify me of updates to Hyaluronan Stimulates Mobilization of Mature Hematopoietic Cells but Not Hematopoietic Progenitors pp. 191-202
Tell A Friend
 
Tell someone you know about this product.
Hyaluronan Stimulates Mobilization of Mature Hematopoietic Cells but Not Hematopoietic Progenitors pp. 191-202 $0.00
Authors:  Ingrid Schraufstatter, Naira Serobyan, Richard DiScipio, Natalia Feofanova, Irina Orlovskaya and Sophia Khaldoyanidi
Abstract:
Mobilization of hematopoietic stem/progenitor cells (HSPCs) is currently a routine clinical procedure that enables the harvesting of HSPCs from peripheral blood and their further use for transplantation and tissue regeneration. Despite of the recent progress in HSPC mobilization strategies, it is generally agreed that further improvement of mobilization protocols is needed to achieve a better quantity and quality of harvested HSPC in a higher percentage of donors (Pelus 2008).
The protocols for HSPC mobilization are based on understanding the molecular mechanisms that regulate homing of these cells into the bone marrow and their retention within the niche. In particular, several chemokines, cytokines, growth factors, their receptors, adhesion molecules as well as hormones and proteases have been identified as contributors to the complex network that regulates migration of HSPCs (Lapidot and Petit 2002; Cottler-Fox, Lapidot et al. 2003; Levesque and Winkler 2008; Pelus 2008; Schulz, von Andrian et al. 2009). Apparently, agents used for HSPC mobilization interrupt these pathways and enable HSPC to detach from the niche, migrate through the matrix, egress from the bone marrow and enter the circulation. 


Available Options:
Version:
This Item Is Currently Unavailable.
Special Focus Titles
01.Medical Cannabis: Clinical Practice
02.Hemorrhagic Shock: Recognition, Pathophysiology and Management
03.Patellofemoral Pain: An Evidence-Based Clinical Guide
04.Neanderthals in Plato’s Cave: A Relativistic Approach to Cultural Evolution
05.My Patients Were Mummies
06.‘L’Atelier Moderne’: An Exploration of the Collaborative Process Between Performer and Composer in Vocal Music Theatre of the 21st Century (CD Included)
07.The Voice at the End of the Telephone Line: The Psychology of Tele Carers
08.Caught up in the Spirit! Teaching for Womanist Liberation
09.The Transgender Handbook: A Guide for Transgender People, Their Families and Professionals
10.Mastering Science with Metacognitive and Self-Regulatory Strategies: A Teacher-Researcher Dialogue of Practical Applications for Adolescent Students
11.Political Migrations in Poland in the Period of World War II
12.Sociolinguistic Parallels Across Europe: Focus on Lowland Scotland and the Eastern Slavic Countries

Nova Science Publishers
© Copyright 2004 - 2017

Hyaluronan Stimulates Mobilization of Mature Hematopoietic Cells but Not Hematopoietic Progenitors pp. 191-202