Nova Publishers
My Account Nova Publishers Shopping Cart
HomeBooksSeriesJournalsReference CollectionseBooksInformationSalesImprintsFor Authors
            
  Top » Catalog » Books » Biology » Cell Biology » Endocytosis: Structural Components, Functions and Pathways Chapters » My Account  |  Cart Contents  |  Checkout   
Quick Find
  
Use keywords to find the product you are looking for.
Advanced Search
What's New? more
Homeland Security: Perceptions, Threats and Challenges
$82.00
Shopping Cart more
0 items
Information
Shipping & Returns
Privacy Notice
Conditions of Use
Contact Us
Notifications more
NotificationsNotify me of updates to SIALIC ACIDS AS MODULATORS OF ENDOCYTOSIS: THE CASE OF DENDRITIC CELLS pp. 161-175
Tell A Friend
 
Tell someone you know about this product.
SIALIC ACIDS AS MODULATORS OF ENDOCYTOSIS: THE CASE OF DENDRITIC CELLS pp. 161-175 $100.00
Authors:  M. Guadalupe Cabral, Hélio J. Crespo, A. Rita Piteira, Dário Ligeiro, Paula A.Videira, CEDOC, Departamento de Imunologia, Faculdade de Ciências Médicas, FCM, Universidade Nova de Lisboa, Lisboa, Portugal, and others
Abstract:
Sialic acids are a family of sugars, which typically terminate cell surface glycoconjugates. Due to this ubiquitous position, they represent key structural determinants for a number of receptors, and are potential modulators of immune responses, among which endocytosis.
Dendritic cells (DC) are professional antigen-presenting cells, crucial for linking innate and immune responses, and have been exploited as therapeutic tools to trigger immunity against tumors or pathogens, or dampen hypersensitivity responses. DCs show a wide capacity to acquire exogenous antigens through different mechanisms, which dictates its immunoregulatory capacity. This chapter focus on the complex role of their highly sialylated cell surface content as modulator of DC endocytosis. In particular it will be presented data that support the evidence that sialylation shortage, while affecting DC maturation, results in opposing effects on macropinocytosis and phagocytosis mechanisms mediated by DCs. 


Available Options:
Version:
This Item Is Currently Unavailable.
Special Focus Titles
01.The Andes: Geography, Diversity, and Sociocultural Impacts
02.Nova Spring 2017 Catalog
03.Amazonian Apple Snails
04.Research on University Teaching and Faculty Development: International Perspectives
05.Factors Affecting Academic Performance
06.Distance Learning: Perspectives, Outcomes and Challenges
07.The Art of Neuroendocrinology: A Case-Based Approach to Medical Decision-Making
08.Beautiful Skin: A Dermatologist's Guide to a Younger Looking You
09.Healing the Mind - Alzheimer’s Disease - Thinking Patents (1983-2007)
10.Rethinking Aging: Foucault, Victims and Death
11.Rainbow Inspirations in Art: Exploring Color as a Metaphor in Poetry, Visual Art and Music
12.Energy Policies of Turkey During the Erdogan Era: Facts and Lies

Nova Science Publishers
© Copyright 2004 - 2017

SIALIC ACIDS AS MODULATORS OF ENDOCYTOSIS: THE CASE OF DENDRITIC CELLS pp. 161-175