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Brain-Cancer Associated Tumor Marker Genes Expression Pattern in Humans
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Authors: Harun M. Said, Adrian Staab and Carsten Hagemann (University of Würzburg, Würzburg, Germany) 
Book Description:
Hypoxia is an important phenomenon possessing a significant correlation with tumour progression, treatment results and the overall disease prognosis. Tumor oxygenation state leads to a series of genomic changes, enabling tumor cells survival or overcoming the oxygen deficient environment conditions. Tumor tissue growth requires a sufficient oxygen and nutrients supply. Tumor cell responses to hypoxic stress include adaptive proteomic changes allowing the cells to overcome nutritive deprivation or to escape their hostile environment by proliferation, invasion, or metastatic spread. Tumor cell proliferation requires rapid synthesis of macromolecules including lipids, proteins, and nucleotides. This book will supply information regarding this pattern in brain cancer.

Imprint: Nova Biomedical



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Table of Contents:
Preface vii
Introduction and Background ix
Chapter 1 Biochemistry of Human Brain Tumor Cells 1
Chapter 2 Glycolytic Regulation in Human Brain Tumors 9
Chapter 3 Hypoxia Induced HiF-1 Gene Regulation in Human Glioblastoma 11
Chapter 4 Regulation via other Hypoxia Gene Regulators 25
Conclusions 27
Acknowledgments 29
References 31
Index 47

   Series:
      Cancer Etiology, Diagnosis and Treatments
   Binding: Softcover
   Pub. Date: 2011 - 2nd quarter
   Pages: 6 x 9
   ISBN: 978-1-61728-011-5
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
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Brain-Cancer Associated Tumor Marker Genes Expression Pattern in Humans