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DNA Damage Repair, Repair Mechanisms and Aging $145.00
Editors: Allison E. Thomas
Book Description:
The preservation of expected life span and longevity, as well as the assurance of life succession among all species requires the integrity and faithful transcription of DNA. A dedicated machinery of DNA repair factors is responsible for reversing DNA damage across the genome. Efficient response to various effectors of DNA damage is also dependent on a complex network of sensors and mediators of stress signals which are upstream of DNA repair activation and together constitute components of the DNA damage response (DDR). This book reviews research on cell cycle checkpoints as essential mechanisms for safeguarding genome stability; nucleotide excision repair (NER) which recognizes and removes bulky DNA damage that leads to DNA double-helix distortion and others.

Table of Contents:
Preface

DNA Instability in Premature Aging
(Lynne S. Cox, Ivan Boubriak, Department of Biochemistry, University of Oxford, South Parks Road, Oxford, United Kingdom)

Recent Advances on DNA Damage, its Repair and Genomic Stability of Green Algae Chlamydomonas Reinhardtii and other Photoautotrophic Eukaryotes
(Andrea Sevcovicova, Alena Hercegova, Dept of Genetics, Faculty of Natural Sciences, Comenius University Bratislava, Slovak Republic)

Intra S-Phase Checkpoint
(Deborah Ruth Tasat, J. Sebastian Yakisich, Universidad Nacional de San Martín Buenos Aires, Argentina, and others)

Multiplex Cell Free Assays to Apprehend DNA Repair Responses: Application to Aging Study
(Sylvie Sauvaigo, Anne-Laure Raffin, Jean-François Millau, Alex Nkengne, Thierry Oddos, Laboratoire Lésions des Acides Nucléiques, LCIB (UMR-E3 CEA-UJF), CEA Grenoble, INAC SCIB LAN, Grenoble, France, and others)

Involvement of the cell cycle inhibitor p21CDKN1A in DNA repair ^
(Micol Tillhon, Ornella Cazzalini, Lucia A. Stivala, A. Ivana Scovassi, Ennio Prosperi, Istituto di Genetica Molecolare del CNR (IGM-CNR), Pavia, Italy. 2Dipartimento di Medicina Sperimentale, Università di Pavia, Pavia, Italy)

7, 8-Dihydro-8-oxoguanine, A Major Form of Oxidative DNA Damage, and its Repair System
(Takeshi Hirano, Department of Life and Environment Engineering, Faculty of Environmental Engineering, The University of Kitakyushu, Kitakyushu, Fukuoka, Japan)

Participation of Heat Shock Proteins in DNA Repair Mechanisms in Cancer
(Silvina Nadin, Daniel R. Ciocca, Laboratory of Tumor Biology (SN) and Laboratory of Oncology (DRC), Institute of Medicine and Experimental Biology of Cuyo, Scientific and Technological Center of Mendoza, National Research Council (CONICET) and Argentine Foundation for Cancer Research, Mendoza, Argentina)

DNA Damage Repair in Testicular Germ Cells of Aging Men
(Moetaz El – Domyati, Hasan El- Fakahany, Denny Sakkas, Department of Dermatology, STD's and Andrology, Al-Minya University, Al-Minya, Egypt, and others)

Nucleotide-Excision Repair Deficiency: A Causative Factor for Accelerated Aging Diseases in Humans?
(Ming Yin, Qingyi Wei, Departments of Epidemiology, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas)

Historical Development of Uncaria Preparations and their Related Bioactive Components
(Ronald W. Pero, Institute of Clinical Medical Sciences, Section of Immunology, Lund University, Lund, Sweden)

DNA Damage Response and Repair: Mechanisms in Aging and Cancer
(Panagiotis J. Vlachostergios, Ioannis A. Voutsadakis, Department of Medical Oncology, University Hospital of Larissa, University of Thessaly School of Medicine, Larissa, Greece)

DNA Repair Gene XPC Codon 939 Polymorphism and AFB1-Related Hepatocellular Carcinoma Risk in Guangxi Population, China
(Xi Dai Long, Yuan-Feng Zhou, Jin-Guang Yao, Pinhu Liao, Yu-Jin Tang, Zan-Song Huang, Bing-Pu Chen, Xiao-Ying Huang, Chao Wang, Ai-Ming Ma, Yun Yi, Qiu-Xiang Liang, Yun-Long Lu, Department of Pathology, Affiliated Hospital of Youjiang Medical College for Nationalities, Baise, Guangxi Zhuang Autonomous Region, China, and others)

Influence of Age on Expresión of DNA Repair Genes in Arabidopsis
(Megan J. Osmond, Bernard A. Kunz, School of Life and Environmental Sciences, Deakin University, Geelong, Victoria, Australia, and others)

Index

   Series:
      DNA and RNA: Properties and Modifications, Functions and Interactions, Recombination and Applications
   Binding: ebook
   Pub. Date: 2010 - 3rd Quarter
   Pages: 7 x 10
   ISBN: 978-1-61728-055-9
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
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