RELATIONSHIP BETWEEN COGNITIVE FUNCTIONING AND QUALITY OF LIFE IN HIV INFECTION, pp. 71-93
Authors: Yogita Rai and Tanusree Dutta
Abstract: HIV/AIDS is one of the life threatening chronic disease. Neurocognitive impairment is a relative common manifestation of HIV infection and it adversely affects quality of life. This article reviewed how HIV infection influences cognitive functioning, which are the major areas of cognition influenced by HIV infection and in which stage do these cognitive impairments occur. It also explored which domain of quality of life is influenced by HIV infection. In this review, the interrelationship between quality of life and cognitive impairment in HIV infection was also reviewed. This review also discussed the significant gaps in the research. Relevant articles were identified and reviewed which related to cognitive functioning and quality of life from 1986 to 2008. There is a lack of consensus among researches with respect to the decline of cognitive functioning among different HIV infected group. Occurrence of cognitive impairment in later stage of infection is well documented but controversy also exists with respect to cognitive impairment in asymptomatic stage of infection. It was found that cognitive functions that are affected in HIV patient include impairment in concentration, memory, thinking, speech, emotional expression, social behavior, the ability to focus on specific stimuli, coordination and information processing. Determining the quality of life of HIV/AIDS patient is important for estimating the burden of the disease. Various studies suggest that cognitive functioning and quality of life are related. The importance of the study lies basically in it‘s ability to identify the areas of cognitive impairment so that appropriate clinical interventions at the right time can be implemented thereby improving the quality of life, and moreover quality of life assessments are important for developing appropriate services and policies.