Nova Publishers
My Account Nova Publishers Shopping Cart
HomeBooksSeriesJournalsReference CollectionseBooksInformationSalesImprintsFor Authors
            
  Top » Catalog » Books » Biology » Biology - General » Cytoskeleton: Cell Movement, Cytokinesis and Organelles Organization Chapters » My Account  |  Cart Contents  |  Checkout   
Quick Find
  
Use keywords to find the product you are looking for.
Advanced Search
What's New? more
Mexico’s Oil and Gas Industry: Considerations, Reform Issues, and U.S. Interests
$120.00
Shopping Cart more
0 items
Information
Shipping & Returns
Privacy Notice
Conditions of Use
Contact Us
Notifications more
NotificationsNotify me of updates to The Myosin Light Chain-IQGAP Interaction: What is its Function? pp. 139-148
Tell A Friend
 
Tell someone you know about this product.
The Myosin Light Chain-IQGAP Interaction: What is its Function? pp. 139-148 $100.00
Authors:  David J Timson
Abstract:
The first members of the IQGAP family of proteins were
characterised over 15 years ago. It is now known that these molecules act
at the interface between cellular signalling pathways and the actin
cytoskeleton. They bind to a diverse range of signalling molecules –
including those involved in calcium, GTPase, kinase and growth factor
signalling. One intriguing interaction is that between mammalian
IQGAP1 and the myosin essential light chain isoform, Mlc1sa. Although
this has been demonstrated in vitro, its in vivo role is not known. Indeed,
it would be tempting to dismiss it as an experimental artefact, except for
the existence of a parallel interaction in the budding yeast,
Saccharomyces cerevisae. In this organism, the IQGAP-like protein
(Iqg1p) interacts with a myosin essential light chain (Mlc1p). This interaction is critical for the correct execution of cytokinesis. IQGAP-like
proteins also play key roles in cytokinesis in other fungi. Recent work
implicating mammalian IQGAP1 in cytokinesis may help explain the role
of the interaction in higher eukarytotes. 


Available Options:
Version:
Special Focus Titles
01.Human Health and Nutrition: New Research
02.Neural Network Learning in Humans
03.The Ophthalmology Clinical Trials Handbook
04.The Big Slide: The Digestive System from Top to Bottom
05.Parenthood and Parenting in Croatia: A Developmental and Socio-Cultural Perspective
06.Parenting: Behaviors, Cultural Influences and Impact on Childhood Health and Well-Being
07.Vygotsky and Leontiev: The Construction of a Marxist Psychology
08.The Politics of Cooperation and Co-ops: Forms of Cooperation and Co-ops, and the Politics that Shape them
09.Nutrition of Crop Plants
10.The Other Side of Italy: Immigration in a Changing Country
11.Investigating Financial Crime: Characteristics of White-Collar Criminals
12.Social Capital: Global Perspectives, Management Strategies and Effectiveness

Nova Science Publishers
© Copyright 2004 - 2015

The Myosin Light Chain-IQGAP Interaction: What is its Function? pp. 139-148