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Development of New MDR-Tuberculosis Drugs
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Authors: Jarmila Vinšová and Martin Krátký (Charles University, the Czech Republic) 
Book Description:
The emergence of resistance to anti-tuberculosis drugs, particularly of MDR-TB and newly XDR-TB, has become a major public health problem. The current treatment regiment has several disadvantages, i.e. long treatment period (DOTS takes minimum 6 months) during which tubercle bacilli mutant become resistant to one or more drugs; side effects of the used drugs; co-infection of HIV/AIDS. The emergence of MDR-TB has made many currently available anti-TB drugs ineffective. Sleeping latent forms of mutant bacilli resistant against common anti-TB drugs pose the risk of epidemic for the new generation. This book outlines the recent advances in the development of new multi-drug-resistant tuberculosis (MDR-TB) drugs.




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Table of Contents:
1. Introduction

2. Resistance to Commonly Used Drugs, Mechanism of the Action, pp. 1-7

3. Research of Novel MDR Potential Drugs, pp. 9-68

4. Conclusion, pp. 69

Index

   Series:
      Pharmacology - Research, Safety Testing and Regulation
   Binding: Softcover
   Pub. Date: 2010
   Pages: 6 x 9
   ISBN: 978-1-61668-233-0
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
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Development of New MDR-Tuberculosis Drugs