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Oxidative Stress and Antioxidants: Their Role in Human Disease $69.00
Editors: Ramon Rodrigo (Faculty of Medicine, Inst. of Biomedical Sciences, University of Chile, Chile)
Book Description:
Oxidative stress is a relatively new concept that has been widely implicated in biomedical sciences during the last 20 years. It significantly participates in the pathophysiology of highly prevalent diseases such as diabetes, hypertension, preeclampsia, atherosclerosis, acute renal failure, Alzheimer and Parkinson diseases, among others. The metabolism of oxygen by cells generates potentially deleterious reactive oxygen species (ROS). Under normal conditions the rate and magnitude of oxidant formation is balanced by the rate of oxidant elimination However, an imbalance between pro-oxidants and antioxidants results in oxidative stress. Increased ROS levels in the cell have a substantial impact either leading to defective cellular function, aging, or disease. Therefore, a better understanding of the roles of ROS-mediated signaling in normal cellular function as well as in disease is necessary for developing therapeutic tools for oxidative stress-related pathologies. The potential beneficial role of antioxidants is discussed in the light of experimental studies, as well as clinical trials aimed to determine the outcome of patients.
“Oxidative Stress and Antioxidants: Their Role in Human Disease” is a practical guide for pathophysiology of oxidative stress and the latest therapeutic advances to modulate the antioxidant defense. This includes evidence from clinical trials, regarding the use of antioxidants and preconditioning, to protect the organism against ROS.
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Table of Contents:
Chapter 1: Oxidative Stress: Basic Overview
(Joaquín Toro and Ramón Rodrigo, Institute of Biomedical Sciences, University of Chile)

Chapter 2: Hypertension
(Ramón Rodrigo)

Chapter 3: Atherosclerosis
(Víctor Molina and Ramón Rodrigo, University of Chile )

Chapter 4: Postoperative Atrial Fibrillation
(José Vinay and Ramón Rodrigo, University of Chile )

Chapter 5: Acute renal failure
(Joaquín Toro, Victor Molina and Ramón Rodrigo, University of Chile)

Chapter 6: Preeclampsia
(Mauro Parra, University of Chile Clinical Hospital)

Chapter 7: Metabolic Syndrome
(Rodrigo Castillo, University of Chile)

Chapter 8: Diabetes Mellitus
(Rodrigo Castillo)

Chapter 9: Nonalcoholic Steatohepatitis
(Juan Gormaz and Ramon Rodrigo, University of Chile)

Chapter 10: Neurodegenerative Disorders
(Rodrigo Pizarro, University of Chile)

Chapter 11: Glaucoma
(Leonidas Traipe, Rodrigo Castillo and Ramón Rodrigo, University of Chile.

Index

   Binding: ebook
   Pub. Date: 2009, 3rd quarter
   ISBN: 978-1-60876-583-6
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
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Oxidative Stress and Antioxidants: Their Role in Human Disease