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Drug-Resistant Tuberculosis: Causes, Diagnosis and Treatments
Retail Price: $205.00
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$184.50
Editors: Shui Ngụy and Zhou K'ung
Book Description:
Tuberculosis (TB) is a major public health problem of global proportions. It is the second leading cause of death from an infectious agent, killing nearly two million people each year, mostly in developing countries. This book outlines the recent advances in the development of new multidrug-resistant tuberculosis (MDR-TB) drugs. The emergence of resistance to antituberculosis drugs, particularly of MDR-TB and newly XDR-TB has become a major health problem. This book provides some glimpses into the current drugs including their mechanism of action, side-effects and mechanism of resistance. The desirable features of new drugs is also discussed, as well as different targets for effective TB treatment and approaches that are being made in the development of potential drugs for resistant tuberculosis. The effectiveness of levofloxacin and olfoxacin in the treatment of multi-drug resistant tuberculosis is also comparatively assessed to determine the immunological effects of certain treatment regimens. Finally, this book expands upon the spectrum of potential resistance-related mutations in MTB clinical isolates to help consolidate the framework for the development of molecular methods for delineating the drug susceptibility profiles in clinical laboratories.

Please click on a chapter below to purchase separately

Chapter 1 - Drug-Resistant Tuberculosis: Causes, Diagnosis and Treatment
Authors / Editors: Suhail Ahmad and Eiman Mokaddas

Chapter 2 - Tuberculosis — The Development of New MDR-TB Drugs
Authors / Editors: Jarmila Vinšová and Martin Krátký

Chapter 3 - Recent Advances towards the Development of New Drugs for Resistant Tuberculosis
Authors / Editors: Ahmed Kamal, Shaik Azeeza and M. Shaheer Malik

Chapter 4 - Molecular Basis of Ethambutol Resistance in Mycobacterium Tuberculosis: Current Insights
Authors / Editors: Igor Mokrousov

Chapter 5 - Drug Resistant Tuberculosis in Bulgaria: Molecular Insights
Authors / Editors: Violeta Valcheva, Nadya Markova, Nalin Rastogi et al.

Chapter 6 - Administration of TB Drugs in Resistance Cases Based on Bacterial Gene Expression Profiling
Authors / Editors: Li M. Fu

Chapter 7 - A Prospective Assessment of Therapeutic Efficacy and Immune Effects of Levofloxacin and Ofloxacin in Multiple-Drug Resistant Tuberculosis
Authors / Editors: Philip Martin Clark, Sule Apikoglu-Rabus, Bayram Kiran, Turan Karagoz, and Fikret Vehbi Izzettin
***Open Access Chapter. Free Download Available***

Chapter 8 - Clinical and Pathomorphological Aspects of Tuberculosis in Hungary
Authors / Editors: György Losonczy and Klára Törő

Chapter 9 - Management of Multidrug-Resistant Tuberculosis – Back to the Future?
Authors / Editors: Wing-Wai Yew and Chen-Yuan Chiang

Chapter 10 - Genetic and Phenotypic Characterization of Drug-Resistant Mycobacterium Tuberculosis Isolates
Authors / Editors: Maysaa El Sayed Zaki

Chapter 11 - Tuberculosis Treatment Failure: Causes and Solutions
Authors / Editors: Philip Martin Clark and Sule Apikoglu-Rabus

Chapter 12 - Approach to Diagnosis and Treatment of Multidrug-Resistant Tuberculosis in the Czech Republic
Authors / Editors: Vaclava Bartu

   Series:
      Virology Research Progress
   Binding: Hardcover
   Pub. Date: 2009
   Pages: 7 x 10, 328 pp.
   ISBN: 978-1-60876-055-8
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
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Drug-Resistant Tuberculosis: Causes, Diagnosis and Treatments