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01.High Levels of Active 1,25-Dihydroxyvitamin D Despite Low Levels of the 25-Hydroxyvitamin D Precursor - Implications of Dysregulated Vitamin D for Diagnosis and Treatment of Chronic Disease (pp. 1-23)
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Handbook of Vitamin C Research: Daily Requirements, Dietary Sources and Adverse Effects
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Editors: Hubert Kucharski and Julek Zajac
Book Description:
The 6-carbon lactone known as ascorbic acid (vitamin C) is an important water-soluble vitamin. It is essential for preserving optimal health and it is used by the body for many purposes, including collagen biosynthesis, melanin reduction and enhanced immunity. This book addresses some important issues related to various methods which are employed to encapsulate asorbic acid. A comparation of the characteristics of ascorbic acid nano and microparticles prepared by different methods is also given. Furthermore, the biomedical significance of human vitamin C metabolism is examined, in the light of polymorphisms in xenobiotic enzymes deduced from genetic, biochemical and epidemiological results to estimate optimal nutrition. Additionally, Vitamin C exerts a protective role against some types of cancer. For that reason, this book investigates the protective effect of vitamin C. Possible pro- and antioxidant effects of vitamin C is also presented and their extrapolation on human health is discussed. Other chapters in this book include a review of the role of vitamin C in the physiology of several diseases, good dietary sources of vitamin C, a study of the effects of environmental tobacco smoke (ETS) on vitamin C status in exposed populations and the role of vitamin C in human reproduction and its effect on people who suffer from epileptic seizures.

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Table of Contents:

Impact of Vitamin C on Exercise-Induced Oxidative Stress and Tissue Injury;pp. 1-43
(Kelsey H. Fisher-Wellman, Richard J. Bloomer, University of Memphis, Memphis, TN)

Human Specific Vitamin C Metabolism and Xenobiotic Polymorphism: The Optimal Nutrition;pp. 45-85
(Yasuo Kagawa, Shizu Higasa, Masaru Tsujimura, Fumio Komatsu, Yoshiko Yanagisawa, Sadahiko Iwamoto, High Technology Center, Kagawa Nutrition University, Sakado, Japan, and others)

Vitamin C Protects from Oxidative DNA Damage and Apoptosis Caused by Food N-Nitrosamines;pp. 87-125
(Ana I. Haza, Almudena García, Paloma Morales, Universidad Complutense de Madrid, Madrid, Spain)

Vitamin C: Dietary Requirements, Dietary Sources, and Adverse Effects;pp.127-152
(Chin-San Liu, Changhua Christian Hospital, Vascular and Genomic Center, Neurology Dept., Chang Jung Christian Univ.)

Pro-Oxidant vs. Antioxidant Effects of Vitamin C;pp. 153-183
(Borut Poljsak, John G. Ionescu, University College of Health Studies, University of Ljubljana, Slovenia, and others)

Encapsulation Devices for Vitamin C;pp. 185-211
(Magdalena Stevanović, Dragan Uskoković, Institute of Technical Sciences of the Serbian Academy of Sciences and Arts, Belgrade, Serbia)

Molecular Bases of the Cellular Handling of Vitamin C: Transport and Metabolism in Health and Disease;pp. 213-236
(Marin J.J.G., Serrano M.A., Perez M.J., Macias R.I.R., Laboratory of Experimental Hepatology and Drug Targeting, Research Unit, University Hospital, Biomedical Research Center for the Study of Liver and Gastrointestinal Diseases, (CIBERehd), Instituto de Salud Carlos III, University of Salamanca, Salamanca, Spain)

Vitamin C: Daily Requirements, Dietary Sources and Adverse Effects;pp. 237-259
(Jun Yang, Jiaren Liu, John Parry, Frito-Lay R&D, Plano, TX, and others)

Vitamin C Intake: Types of Foods Consumed and Meal Pattern Differences in Children with High or Low Exposure to Environmental Tobacco Smoke;pp. 261-279
(Alan M. Preston, Luis Vásquez Quiñones, Cynthia M. Pérez, Ernesto Pérez Torres and Cinty Rodríguez, University of Puerto Rico)

The Role of Vitamin C in Human Reproduction;pp. 281-297
(Tzagaraki E., Sofocleous C., Tounta G., Mavrou A., Kolialexi ., Department of Medical Genetics, Athens University School of Medicine, Athens, Greece)

Effects of Vitamin C on Oxidative Stress-Induced Molecular Pathways in Epilepsy;pp. 299-312
(Mustafa Nazıroğlu, Süleyman Demirel University, Isparta, Turkey)

Vitamin C as a Stress Bioindicator of Norway Spruce: A Case Study in Slovenia;pp. 313-328
(Samar Al Sayegh Petkovšek, Boštjan Pokorny, Erico Velenje, Ecological Research and Industrial Cooperation, Velenje, Slovenia)

Protective Effect of Vitamin C on Vascular Damage and Arterial Hypertension Induced by Low-Level of Mercury and Lead Exposure;pp. 329-341
(Antonio J. López-Farré, José J. Zamorano-León, Daniel Sacristán, Maria Marques, and Carlos Macaya, Alberto Barrientos, Hospital Clinico San Carlos, Madrid, Spain)

Vitamin C in the Treatment of Endothelial Dysfunction;pp. 343-354
(Alin Stirban, Diabetes Clinic, Ruhr- University Bochum, Bad Oeynhausen, Germany)

Vitamin C Intake by Japanese Patients with Chronic Obstructive Pulmonary Disease;pp. 355-366
(Fumi Hirayama and Andy H. Lee, School of Public Health, Curtin University of Technology, Perth, Australia)

Reciprocal Effects of Ascorbate on Cancer Cell Growth and the Expression of Matrix Metalloproteinases and Transforming Growth Factor-Beta: Modulation by Gene Silencing or P. Leucotomos;pp. 367-375
(Neena Philips, School of Natural Sciences, Fairleigh Dickinson University, Teaneck, NJ, USA)

Shortage of Vitamin C Accelerates Aging;pp. 377-383
(Akihito Ishigami, Department of Biochemistry, Faculty of Pharmaceutical Sciences, Toho University, Chiba, Japan)

The Importance of Food Processing on Vitamin C: Present and Future Trends;pp. 385-388
(Rui M. S. Cruz, Margarida C. Vieira, Cristina L. M. Silva, Escola Superior de Biotecnologia, Universidade Católica Portuguesa, Portugal, and others)

Index pp.389-415

      Nutrition and Diet Research Progress
   Binding: Hardcover
   Pub. Date: 2009
   Pages: 415 pp.
   ISBN: 978-1-60741-874-0
   Status: AV
Status Code Description
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PR At Prepress
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Handbook of Vitamin C Research: Daily Requirements, Dietary Sources and Adverse Effects