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Progress in Neurodegeneration: The Role of Metals
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Editors: Maria Rosa Avila-Costa ( Universidad Nacional Autonoma de Mexico (UNAM) Veronica Anaya Martinez ( Universidad Nacional Autonoma de Mexico (UNAM),
Book Description:
This book highlights the role of some metals which induce oxidative stress and imbalances in the neurodegenerative diseases such as Alzheimer disease, Parkinson disease, Amyotrophic Lateral Sclerosis, Huntington Disease, and other dementias. The chemistry and biochemistry of metals induced-oxidative stress, protein damage is first described, followed by the evidence for a pathological role of oxidative stress in these disease states. It is tempting to speculate that free radical oxygen chemistry contributes to pathogenesis in all these conditions, though it is as yet undetermined what types of oxidative changes occur early in the disease, and what types are secondary manifestations of neuronal degeneration. Finally the authors review different metals to describe their specific role in the different pathologies.

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Table of Contents:
1. The Newvous System and Brain Damage pp. 1-14
(Maria Rosa Avila-Costa1, Leonardo la-Costa1, Leonardo Reynoso-Erazo2, Ana Luisa Gutierrez-Valdez1, Jose Luis Ordoñez-Librado1. 1.Dept. of Neuroscience, Neuromorphology Lab; 2Health Education Team, UNAM, Mexico

2. Neurodegenerative Diseases pp. 15-46
(Maria Rosa Avila-Costa1, Leonardo Reynoso-Erazo2, Ana Luisa Gutierrez-Valdez1, Jose Luis Ordoñez-Librado1. 1Dept. of Neuroscience, Neuromorphology Lab; 2Research Division, Health Education Team. UNAM, Mexico

3. Metals, Toxicity AND Neurodegeneation pp. 47-90
(Maria Rosa Avila-Costa1, Leonardo Reynoso-Erazo2, Ana Luisa Gutierrez-Valdez1, Jose Luis Ordoñez-Librado1. 1Dept. of Neuroscience, Neuromorphology Lab; 2Research Division, Health Education Team. UNAM, Mexico)

4. Aluminum pp. 91-118
(Maria Rosa Avila-Costa1, Laura Colín-Barenque1, Leonardo Reynoso-Erazo2, Ana Luisa Gutierrez-Valdez1, Jose Luis Ordoñez-Librado1. 1Dept. of Neuroscience, Neuromorphology Lab; 2Research Division, Health Education Team. UNAM, Mexico)

5. Manganese pp. 119-143
(Jose Luis Ordoñez-Librado, Neuromorphology Lab. UNAM, Mexico)

6. Cadmium pp. 145-173
(Jose Luis Ordoñez-Librado, Maria Rosa Avila-Costa. Dept. of Neuroscience, Neuromorphology Lab. UNAM, Mexico)

7. Zinc pp. 175-207
(Ricardo García-Ruiz. Dept. of Neuroscience, Neuromorphology Lab. UNAM, Mexico)

8. Vanadium pp. 209-226
(Maria Rosa Avila-Costa. Dept. of Neuroscience, Neuromorphology Lab. UNAM, Mexico)

9. Lead pp. 227-251
(Ana Luisa Gutierrez Valdez. Dept. of Neuroscience, Neuromorphology Lab. UNAM, Mexico)

10. Iron pp. 253-279
(Maria Rosa Avila-Costa, José Luis Ordoñez-Librado, Ana Luisa Gutierrez-Valdez, Enrique Montiel-Flores. Dept. of Neuroscience, Neuromorphology Lab. UNAM, Mexico)

11. Mercury pp. 281-318
(Maria Luisa Juárez Seres, Ana Luisa Gutierrez-Valdez, Maria Rosa Avila-Costa. Dept. of Neuroscience, Neuromorphology Lab. UNAM, Mexico)

12. Copper pp. 319-343
(Verónica Anaya-Martínez, Maria Rosa Avila-Costa. Dept. of Neuroscience, Neuromorphology Lab. UNAM, Mexico)

Index

   Series:
      Neurodegenerative Diseases - Laboratory and Clinical Research
   Binding: Hardcover
   Pub. Date: 2009
   Pages: 382 pp.
   ISBN: 978-1-60741-317-2
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
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Progress in Neurodegeneration: The Role of Metals