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Historical Overview of Chromatography and Related Techniques in Analysis of Antimalarial Drug Primaquine
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Authors: Ilia Brondz (University of Oslo, Norway) 
Book Description:
Every year, more than one million children die from malaria in sub-Saharan Africa alone, and about 500 million new cases are registered worldwide annually. Today, malaria is not longer limited to poor areas of world, but has returned to southern European countries, such as Italy, France, and some countries in the Caucasus. Children are most vulnerable to this disease, and in Africa, childhood deaths from malaria account for about 90% of the total human deaths from this disease. Primaquine has strong antiparasitic effects against the malarial gametocytes and therefore prevent the spread of the parasite to mosquitoes from infected patients undergoing treatment. This book examines the problems related to malaria and antimalarial drugs. (Imprint: Nova)

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Table of Contents:
Chapter I. History of malaria pp.1-12

Chapter 2. Discovery and introduction of natural and synthetic antimalarial drugs and agents relevant to the suppression of the malaria mosquito pp.13-40

Chapter 3. Pharmacopeias: their history and place in drug quality control pp.41-54

Chapter 4. Analytical quantitative measurements pp.55-64

Chapter 5. Discovery and development of chromatography pp.65-80

Chapter 6. Planar chromatography or Open-bed chromatography as a tool for the qualitative and quantitative analysis of primaquine pp.81-88

Chapter 7. High-performance liquid chromatography (HPLC pp.89-105

Chapter 8. Supercritical fluid chromatography (SFC pp.106-126

Chapter 9. Gas chromatography (GC) and gas chromatography - mass spectroscopy pp.127-149

Chapter 10. Spectroscopy and spectrometry pp.150-170

Chapter 11. In search of antimalarial drugs in the 8-methoxyaminoquinoline pp.171-184

Chapter 12. Who’s who in the world struggle to curb malaria pp.185-200

Chapter 13. The Via Dolorosa (the Way of Grief or Suffering)pp.201-211

Acknowledgments pp.213-214

Index pp.215-222

      Tropical Diseases - Etiology, Pathogenesis and Treatments
      Pharmacology - Research, Safety Testing and Regulation
   Binding: Hardcover
   Pub. Date: 2011 - 2nd quarter
   Pages: 222.pp
   ISBN: 978-1-61761-944-1
   Status: AV
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
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Historical Overview of Chromatography and Related Techniques in Analysis of Antimalarial Drug Primaquine