Nova Publishers
My Account Nova Publishers Shopping Cart
HomeBooksSeriesJournalsReference CollectionseBooksInformationSalesImprintsFor Authors
            
  Top » Catalog » Books » Biology » Aging » My Account  |  Cart Contents  |  Checkout   
Quick Find
  
Use keywords to find the product you are looking for.
Advanced Search
What's New? more
Bread: Consumption, Cultural Significance and Health Effects
$160.00
Shopping Cart more
0 items
Information
Shipping & Returns
Privacy Notice
Conditions of Use
Contact Us
Bestsellers
01.The Closing Chapters of Long Lives: Results from the 10-Year Swilsoo Study on the Oldest Old
02.Alzheimer's Disease in the Middle-Aged
03.Aging and Age-Related Diseases: The Basics
04.New Research on Nutrition for the Middle-Aged and Elderly
05.Progress in Cell Cycle Control Research
06.Foucault and Aging
07.Handbook of Cognitive Aging: Causes, Processes and Effects
08.Handbook of Type 2 Diabetes in the Middle Aged and Elderly
09.Old Age and Agency
10.Aging and the Elderly: Psychology, Sociology, and Health
Notifications more
NotificationsNotify me of updates to Human Chromosomes and Aging: From 80 to 114 Years
Tell A Friend
 
Tell someone you know about this product.
Human Chromosomes and Aging: From 80 to 114 Years
Retail Price: $130.00
10% Online Discount
You Pay:

$117.00
Authors: Teimuraz Lezhava (Tbilisi State University, Georgia) 
Book Description:
This book presents a comprehensive review of the morphology and function of chromosomes in elderly people. The wide range of topics includes cyclical chromosome properties, mutations, repair, progressive chromosome heterochromatinization with increasing age, roles of nucleolar organizer regions, sister chromatid exchanges, homolog relationships, heterochromatin regions and other chromosomal features in very old age. This ground-breaking book focuses on heterochromatinization as a key determinant of the genetic apparatus function during senescence and an area to seek life-prolonging interventions. The book illustrates and updates progress in the field of cytogenetics of aging. The book contains 16 tables and 25 figures.

Table of Contents:
Chapter Availability

Individual chapters are available for $25 each by sending an email to novascience@earthlink.net. Nova will provide the chapter for your easy downloading or send it as an email attachment if you prefer.

Foreword
Introduction
CHAPTER 1 - Genetic Basis of Aging
1.1- General Considerations
1.2- Theory of Aging
CHAPTER 2 - Mutation
2.1- Aneuploidy
2.1.1- Aneuploidy in Peripheral Lymphocyte Cultures
2.1.2- Relationship Between ‘Natural’ and ‘Artifactual’ Aneuploidy
2.1.3- Premature Disjunction of Centromeres
2.1.4- Polyploidy (Endoreduplication)
2.2- Aberrations
2.2.1- Incidence of Aberrant Cells and Chromosome Aberrations
2.2.2- Types of Chromosome Aberrations
2.2.3- Chromosome Aberrations Induced by Heavy Metal Salts Discussion
Conclusion
CHAPTER 3 - Repair
3.1- Repair of DNA
3.1.1- Repair in Human Congenital Diseases
3.2- Unscheduled DNA Synthesis
3.3- Sister Chromatid Exchanges
Discussion
Conclusion
CHAPTER 4
Chromosome Modification
4.1- Functional Differentiation of Chromatin
4.1.1- Variability of Condensed Chromatin
4.2-Heat Absorption of Condensed Chromatin
4.3-Centromeric Heterochromatin
4.3.1- Y-Chromosome Centromeric Heterochromatin in Longeval Families
4.4- Telomeric Heterochromatin
Discussion
Conclusion
CHAPTER 5
Acrocentric Chromosomes
5.1- Nucleolar Organizer Regions 5.1.1-The Short Arm of the Human Acrocentric Chromosomes: Morphology
5.2- Human Acrocentric Chromosome Associations
5.2.1-Relationship Between the Incidence of Recognizable Satellites, Associations and Age in Group D and G Acrocentric Chromosomes
5.2.2- Satellite Associations and Ag-staining Patterns
5.2.3- Cis- and Trans-types of Chromatid Association
5.3- Transcriptional Activity of Ribosomal Cistrones
Discussion
Conclusion
CHAPTER 6
Chromosome Arrangement
6.1-Chromosome Arrangement in Metaphase Somatic Cells
6.1.1-Distribution of Homologous Chromosome Pairs
1, 2, 3 and 16
Discussion
Conclusion
CHAPTER 7
Deheterochromatinization of Chromosomes
7.1- Peptide Bioregulators Induced Reactivation of Chromatin
7.1.1- Denaturation of Total Heterochromatin
7.1.2- Transcriptional Activity of Ribosomal Genes
7.1.3- Heteromorphism of Structural C-Heterochromatin
7.1.4- Variability of Facultative Heterochromatin (Condensed Euchromatin Regions) Based on SCE Test
Discussion
Conclusion
CHAPTER 8
General Conclusions
8.1- Heterochromatinization of Chromosomes
8.2- Heterochromatinization As a Key Factor in Aging
8.3- Possible Mechanisms of Aging Pathologies References
Glossary
Index

   Binding: Hardcover
   Pub. Date: July 2006
   ISBN: 1-60021-043-0
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
Special Focus Titles
01.The Andes: Geography, Diversity, and Sociocultural Impacts
02.Nova Spring 2017 Catalog
03.Amazonian Apple Snails
04.Research on University Teaching and Faculty Development: International Perspectives
05.Factors Affecting Academic Performance
06.Distance Learning: Perspectives, Outcomes and Challenges
07.The Art of Neuroendocrinology: A Case-Based Approach to Medical Decision-Making
08.Beautiful Skin: A Dermatologist's Guide to a Younger Looking You
09.Healing the Mind - Alzheimer’s Disease - Thinking Patents (1983-2007)
10.Rethinking Aging: Foucault, Victims and Death
11.Rainbow Inspirations in Art: Exploring Color as a Metaphor in Poetry, Visual Art and Music
12.Energy Policies of Turkey During the Erdogan Era: Facts and Lies

Nova Science Publishers
© Copyright 2004 - 2017

Human Chromosomes and Aging: From 80 to 114 Years